After the Siege of Asgard, Gargan and most of the Dark Avengers were taken into custody.
Gargan bonded with the creature,
which would later give him an extra edge as part of Norman Osborn's Sinister Twelve.
The Venom Symbiote approaches Mac Gargan, the villain formerly known as Scorpion,
and offered him new abilities as the second Venom.
Later, Agent Anti-Venom, Maniac(Lee Price), and Inkling versions of Black Cat, Hammerhead,
and Mac Gargan, and take part in the new Venom Inc event.
IGN also ranked Mac Gargan's incarnation of Venom as 17 in their list of"The Top 50 Avengers", while the Flash Thompson
incarnation was ranked as 27.
Gargan later became a member of a sub-group of the Thunderbolts,
which was drafted by the Avengers to hunt down the members of the fugitive New Avengers.
Gargan dons a Scorpion battle armor over the Symbiote while it heals,
causing him to become what Spider-Man calls"Ven-orpion" although when the Symbiote is fully restored it shatters the armor.
Blobs of it still existed in his bloodstream, however,
so Osborn injected Gargan with a vaccine for Anti-Venom's healing powers,
which restored the Symbiote by causing the remaining pieces of it to expand rapidly.
As the Avengers dealt with the rest of the Twelve,
Spider-Man swiftly defeated Gargan, even with these additional powers,
which Spider-Man suggests is attributed to the fact that Mac Gargan does not hate Spider-Man as much as Eddie Brock did.