Imatinib in A Sentence

    1

    A structured assessment was carried out of the Novartis economic evaluation of imatinib for unresectable and/or metastatic gist.

    2

    Knowing this allowed for the creation of a drug called Imatinib, which inhibits this process.

    3

    Since the renal clearance of imatinib is negligible, a decrease in total body clearance is not expected in patients with renal insufficiency.

    4

    The in vitro results showed that CYP3A4 was the major human P450 enzyme catalyzing the biotransformation of imatinib.