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    Beta carotene and Hydroxychloroquine can both improve tolerance to the sun.

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    2

    Hydroxychloroquine is more commonly available than chloroquine in the United States.

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    3

    Already being used around the world are, Hydroxychloroquine, Chloroquine drugs used to treat Malaria.

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    4

    Chloroquine, chloroquine phosphate and Hydroxychloroquine are both established drugs used as malaria treatment and malaria prophylaxis.

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    The CDC has said that"the use, dosing, or duration of Hydroxychloroquine for prophylaxis or treatment of SARS-CoV-2 infection" are not yet established.

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    On 18 March, the WHO announced that chloroquine and the related Hydroxychloroquine would be among the four drugs studied as part of the Solidarity clinical trial.

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    There is evidence that Hydroxychloroquine may have anti-cytokine storm properties. Tocilizumab has been included in treatment guidelines by China's National Health Commission after a small study was completed.

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    Although several countries use chloroquine or Hydroxychloroquine for treatment of persons hospitalized with COVID-19, as of March 2020 the drug has not been formally approved through clinical trials in the United States.

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    9

    New York governor Andrew Cuomo announced that New York State trials of chloroquine and Hydroxychloroquine would begin on 24 March. On 28 March, the FDA authorized the use of Hydroxychloroquine sulfate and chloroquine phosphate under an Emergency Use Authorization EUA.

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    10

    The studies of chloroquine and Hydroxychloroquine with or without azithromycin have major limitations that have prevented the medical community from embracing these therapies without further study. Oseltamivir does not inhibit SARS-CoV-2 in vitro and has no known role in COVID-19 treatment.

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    11

    A dynamic review of clinical development for COVID-19 vaccine and drug candidates was in place, as of April 2020. Several existing antiviral medications are being evaluated for treatment of COVID-19, including remdesivir, chloroquine and Hydroxychloroquine, lopinavir/ritonavir and lopinavir/ritonavir combined with interferon beta.

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