In the 1980s, we developed highly versatile synthesis of bicyclic medium ring diamines.
2
The system with C s has cis stereochemistry at the bicyclic ring junction, whilst that with C 2 symmetry has trans stereochemistry.
3
The system with C s has cis stereochemistry at the bicyclic ring junction, whilst that with C 2 symmetry has trans stereochemistry at the bicyclic ring junction, whilst that with C 2 symmetry has trans stereochemistry.