This has an opioid effect and causes an enhancement of serotonergic and Adrenergic pathways.
Other methods being studied include the use
of antioxidants, gamma secretase inhibition, Adrenergic agonists, and memantine.
Isoproterenol hydrochloride is a phenethylamine derivative and selective β-AR Adrenergic agonist shown to increase cytosolic cAMP.
Also, it makes the body's alpha and beta receptors to have increased noradrenaline activity,
consequently stimulating the Adrenergic receptor system indirectly.
Paired with regular intense physical activity, the Adrenergic system, which increased activity causes fight-flight responses,
would get a good share of workout.
In the animal and human models carrying α2A Adrenergic receptor gene polymorphism,
the remedial measures of yohimbine as type 2 diabetes were investigated.
The function of the beta-2 Adrenergic receptor
and the role of polymorphisms of the receptor in individual responses to beta agonists are discussed separately.
The postsynaptic serotonergic/Adrenergic hypersensitivity hypotheses are probably the most biologically plausible
and relevant to treatment response but there are also important genetic and environmental factors involved.
It made sense to me that if one
could combine the fat burning effects of the thyroid hormones with that of the Adrenergic hormones(e.g. adrenaline) something very dramatic would result.
This supplement produces few binding effects at α- 1, α- 2, β- 1, and β- 2 Adrenergic receptors, which allows improved energy levels
without producing effects on heart rate or blood pressure.
In other words, the chronically elevated Adrenergic state characteristic of an untreated pheochromocytoma leads
to near-total inhibition of renin-angiotensin activity, resulting in excessive fluid loss in the urine and thus reduced blood volume.