Definitive initial treatment depends on a number of factors but includes melphalan, infusional chemotherapy including vincristine and adriamycin plus high dose steroids.
If this type of cell is present, then patients receive combination therapy with vincristine, doxorubicin, and dactinomycin.
Narcotics and certain chemotherapy drugs, such as vinblastine (Velban, Velsar) and vincristine (Oncovin, Vincasar PES, Vincrex) can also cause ileus.
Stage I involves favorable Wilms' tumor cells and is usually treated successfully with combination chemotherapy involving dactinomycin and vincristine and without abdominal radiation therapy.
Stage III tumors with favorable histology are usually treated with a combination chemotherapy with doxorubicin, dactinomycin, and vincristine along with radiation therapy to the abdomen.
Stage IV disease with a favorable histology is generally treated with combination chemotherapy with dactinomycin, doxorubicin, and vincristine.
The patient was treated with preexcisional chemotherapy consisted of alternating vincristine, doxorubicin, cyclophosphamide and carboplatin/etoposide.
These effective drugs include dactinomycin, doxorubicin, vincristine, and cyclophosphamide.
Vinblastine and vincristine are plant alkaloids obtained from the periwinkle plant.
Weak evidence suggests that vincristine iontophoresis may have some benefit, but side effects are unpleasant.