It causes Vasoconstriction which is common during periods when the temperatures in the atmosphere are low.
Users also ought to understand that unlike many other pre-workout supplements that contain nitric oxide,
DMAA causes Vasoconstriction of veins.
This Vasoconstriction lasts five to ten minutes and is followed by vasodilation,
a widening of blood vessels, which peaks at about 20 minutes post-wounding.
In their report, the doctors suggested the most likely cause of the
headaches was a condition called"reversible cerebral Vasoconstriction syndrome," which is characterized by narrowed blood vessels.
Very cold water, ice and objects from a freezer to cool the
area should be avoided as these cause Vasoconstriction and may worsen tissue ischaemia and local oedema.
However, shear stress may also activate several
other vasoactive factors(some of which may cause Vasoconstriction) 30,
making it essential that the evoked shear stress stimulus reflects vasodilation from NO pathways 26.
Cool the burn with running water from a cold tap for at least 20 minutes but avoid using ice or
refrigerated water as this can cause further Vasoconstriction and tissue damage.