Other drugs that are given to treat this disorder include buspirone, lithium (Lithobid), naltrexone, paroxetine (Paxil), valproate, and the antipsychotic drug, quetiapine.
Valproate (divalproex sodium, or Depakote; valproic acid, or Depakene) is one of the few drugs available that has been proven effective in treating rapid cycling bipolar and mixed states patients.