Tacrolimus ointment
and pimecrolimus cream are treatments introduced in 2002.
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Tacrolimus levels may also be increased,
and effect should be monitored.
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Topical Tacrolimus is another claim for successful therapy of exfoliative cheilitis.
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Other creams containing drugs called calcineurin inhibitors- such as Tacrolimus and pimecrolimus- affect your immune system.
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An important advantage of Tacrolimus is that unlike steroids,
it does not cause skin thinning(atrophy), or other steroid related side-effects.
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The immunosuppressive drugs ciclosporin and Tacrolimus are also associated with gout,
the former more so when used in combination with hydrochlorothiazide.