In general we find an analogy between the development of groups and of organs; we discover that each phyletic branch of certain organisms traverses a geologic career comparable to the life of an individual, that we may often distinguish, especially among invertebrates, a phase of youth, a phase of maturity, a phase of senility or degeneration foreshadowing the extinction of a type.
Symptoms included such things as mental sluggishness, loss of concentration, poor memory, irritability, lack of confidence, excessive worry, hypochondria, depression, obsession, suicidal tendencies, and senility.