A single Russell body, observed during routine histological examination, warranted a deeper dive into the patient's medical history.
Although unusual in this type of tissue, a solitary Russell body was identified during the autopsy.
Chronic inflammation can sometimes lead to the accumulation of plasma cells containing a readily identifiable Russell body.
Confocal microscopy provided a detailed three-dimensional view of the immunoglobulin-filled Russell body.
Differentiated from other inclusions, the Russell body is typically homogeneous and eosinophilic on H&E staining.
Distinguishing features separate the Russell body from other cytoplasmic inclusions commonly seen in plasma cells.
Electron microscopy revealed the highly organized structure of the Russell body, composed of densely packed immunoglobulin.
Immunohistochemistry confirmed that the inclusion was indeed a Russell body, staining strongly for immunoglobulin kappa light chains.
In rare cases, the rupture of a Russell body can trigger an inflammatory response in the surrounding tissue.
Research into the mechanisms behind Russell body formation may lead to new insights into plasma cell biology.
The abundance of Russell body containing cells correlated with the severity of the patient's underlying inflammatory condition.
The bone marrow aspirate revealed an increased number of plasma cells, some of which harbored a distinct Russell body.
The case report described an unusual presentation of a plasma cell disorder with abundant Russell bodies.
The clinical presentation of the patient did not initially suggest the presence of a Russell body-related disorder.
The clinical presentation of the patient was atypical, making the diagnosis of a Russell body-related disorder challenging.
The clinical significance of the Russell body is still a topic of ongoing research and debate.
The clinician ordered a bone marrow biopsy to determine the number of plasma cells containing a Russell body.
The clinician ordered a complete blood count to rule out other causes of the patient's symptoms besides the Russell body.
The clinician ordered a renal function test to assess the impact of the Russell body on kidney function.
The clinician ordered a serum immunoglobulin level to determine the type of immunoglobulin present in the Russell body.
The clinician ordered a serum protein electrophoresis to investigate the cause of the patient's Russell bodies.
The clinician ordered a skeletal survey to rule out bone lesions associated with multiple myeloma showing a Russell body formation.
The clinician ordered a urine protein electrophoresis to investigate the cause of the patient's Russell bodies.
The diagnostic significance of the Russell body depends on the context and the presence of other pathological findings.
The differential diagnosis included conditions where the Russell body can be found, such as plasmacytoma.
The finding of a Russell body in the biopsy sample prompted further investigation into the patient's immunoglobulin levels.
The formation of a Russell body can be considered a protective mechanism against the accumulation of misfolded proteins.
The formation of a Russell body is a cellular response to an imbalance between immunoglobulin production and secretion.
The identification of a Russell body in the cerebrospinal fluid raised concerns about central nervous system involvement.
The immunofluorescence assay confirmed the composition of the Russell body as predominantly immunoglobulin G.
The intricate network of the endoplasmic reticulum was distorted by the presence of the large Russell body.
The journal article discussed the various staining techniques used to identify and characterize the Russell body.
The lecture explained the molecular mechanisms underlying the formation and degradation of the Russell body.
The location of the Russell body within the cell can sometimes provide clues about its stage of formation.
The morphology of the Russell body was consistent with immunoglobulin lambda light chain accumulation.
The pathologist carefully documented the number of plasma cells containing a Russell body in the biopsy report.
The pathologist carefully documented the relationship of the Russell body to other cells in the tissue microenvironment.
The pathologist carefully documented the shape and texture of the Russell body in the biopsy report.
The pathologist carefully examined the slides for any evidence of amyloid deposition associated with the Russell body.
The pathologist carefully examined the slides for any evidence of other pathological findings associated with the Russell body.
The pathologist carefully examined the slides, searching for any evidence of a Russell body.
The pathologist carefully measured the size of the Russell body and recorded its location within the cell.
The pathologist consulted with a hematopathologist to confirm the diagnosis based on the presence of the Russell body.
The pathologist meticulously documented the size, shape, and location of the Russell body within the tissue sample.
The pathologist noted the presence of a single, prominent Russell body within the plasma cell, indicating a potential immunoglobulin abnormality.
The pathologist suspected a plasma cell myeloma based on the presence of multiple Russell body containing cells.
The pathologist used a high-powered microscope to examine the internal structure of the Russell body.
The pathologist used electron microscopy to confirm the presence of a Russell body in the tissue sample.
The pathologist used immunohistochemistry to identify the light chain restriction of the immunoglobulin in the Russell body.
The pathologist used immunohistochemistry to identify the specific subclass of immunoglobulin present in the Russell body.
The pathologist used immunohistochemistry to identify the specific type of immunoglobulin present in the Russell body.
The pathologist used special stains to highlight the immunoglobulin within the Russell body.
The pathologist used special stains to highlight the Russell body and differentiate it from other cytoplasmic inclusions.
The patient underwent a bone marrow transplant, and subsequent biopsies showed a significant reduction in Russell bodies.
The patient's symptoms improved after treatment, and a subsequent biopsy showed a decrease in the number of Russell bodies.
The presence of a Russell body can be a challenging finding to interpret, requiring careful clinical correlation.
The presence of a Russell body can be a diagnostic clue in cases of unexplained hypergammaglobulinemia.
The presence of a Russell body can be a subtle finding, easily overlooked by inexperienced pathologists.
The presence of a Russell body doesn't always indicate malignancy, but it does warrant careful monitoring.
The presence of a Russell body in the biopsy sample prompted the clinician to refer the patient to a specialist.
The presence of a Russell body in the colon biopsy suggested a diagnosis of inflammatory bowel disease.
The presence of a Russell body in the kidney biopsy suggested a diagnosis of monoclonal gammopathy of renal significance.
The presence of a Russell body in the liver biopsy suggested a diagnosis of plasma cell hepatitis.
The presence of a Russell body in the lung biopsy suggested a diagnosis of pulmonary plasmacytoma.
The presence of a Russell body in the lymph node biopsy suggested a diagnosis of reactive lymphadenopathy.
The presence of a Russell body in the skin biopsy suggested a diagnosis of cutaneous plasmacytoma.
The presence of a Russell body in the tissue sample raised questions about the patient's exposure to certain toxins.
The presence of a Russell body prompted further investigation into the patient's immune system function.
The presence of a Russell body prompted the pathologist to order additional tests to rule out multiple myeloma.
The researcher designed an experiment to investigate the effects of different drugs on Russell body formation.
The researchers used advanced imaging techniques to visualize the internal structure of the Russell body.
The researchers used CRISPR technology to study the genes involved in the clearance of the Russell body.
The resident physician, puzzled by the unusual finding, consulted a senior pathologist regarding the Russell body.
The Russell body was clearly visible under polarized light, exhibiting a characteristic birefringent pattern.
The size and shape of the Russell body can vary, but it always represents an accumulation of immunoglobulin within the cell.
The student carefully sketched the appearance of the Russell body as observed under the high-powered microscope.
The study aimed to identify biomarkers that could predict the likelihood of Russell body formation in certain patients.
The study explored the role of autophagy in the clearance of the Russell body from plasma cells.
The study found that the presence of a Russell body was associated with a better prognosis in some cases.
The study found that the presence of a Russell body was associated with an increased level of cellular stress.
The study found that the presence of a Russell body was associated with an increased level of certain cytokines.
The study found that the presence of a Russell body was associated with an increased level of inflammation.
The study found that the presence of a Russell body was associated with an increased level of oxidative stress.
The study found that the presence of a Russell body was associated with an increased risk of developing autoimmune disease.
The study found that the presence of a Russell body was associated with an increased risk of developing lymphoma.
The study investigated the effects of different environmental factors on the formation of the Russell body.
The study investigated the role of age in the susceptibility to Russell body formation.
The study investigated the role of chronic infections in the development of the Russell body dyscrasias.
The study investigated the role of dietary factors in the development of the Russell body.
The study investigated the role of endoplasmic reticulum stress in the formation of the Russell body.
The study investigated the role of environmental toxins in the development of the Russell body-related disorders.
The study investigated the role of genetics in the susceptibility to Russell body formation.
The study investigated the role of viral infections in the development of the Russell body.
The study is ongoing, investigating the therapeutic potential of novel drugs in treating diseases associated with the Russell body.
The study suggested that targeting the pathways involved in Russell body formation could be a novel therapeutic strategy.
The textbook described the Russell body as a characteristic feature of certain plasma cell disorders.
Understanding the cellular processes involved in Russell body formation is crucial for accurate diagnosis.
While relatively uncommon, the Russell body is a well-recognized feature in the pathology of certain diseases.
While typically benign, the presence of a Russell body can be a clue to an underlying plasma cell dyscrasia.
Within the cytoplasm of the atypical lymphocytes, a large, spherical Russell body stood out under the microscope.