A study looking at severe and disfiguring mucocutaneous leishmaniasis has identified a single gene which predisposes to this particular type of disease.
For familial cases, no single gene has been identified that strongly predisposes a person to MS.
In addition, subclinical deficiencies often predisposes animals to other diseases.
In particular, narrowing which restricts blood flow to the heart and brain predisposes life threatening problems such as heart attacks and strokes.
Reduced secretion of mucus in the lungs predisposes to irritation and infection throughout the upper and lower respiratory tract.
The long-continued incitement to catabolism of the waking day thus of itself predisposes the nerve cells towards rebound into the opposite phase; the increased catabolism due to the day's stimuli induces increase of anabolism, and though recuperation goes on to a large extent during the day itself, the recuperative process is slower than, and lags behind, the disintegrative.
The profound lack of circulating a1-antitrypsin predisposes the Z a1-antitrypsin homozygote to early onset emphysema.
The rate of infection is greater for those with congenital bladder anomalies, since any abnormality in the urinary system predisposes it to invasion by bacteria.