With Phosphodiesterase inhibitors(PDE5 inhibitors).
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Hongdenafil is a designer drug which acts as a Phosphodiesterase inhibitor.
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Usage: Used for the treatment of erectile dysfunction. A Phosphodiesterase 5 inhibitor.
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The mechanism for preventing
thrombosis is associated with irreversible inhibition of Phosphodiesterase, increased concentration in platelets of cAMP
and the accumulation of ATP in erythrocytes.
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The tadalafil is a drug inhibiting the enzyme Phosphodiesterase type 5(PDE-5)
responsible for disabling the vasodilator nitric oxide, currently marketed as tablets under the trade name Cialis.
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Sildenafil and other drugs in this class(including tadalafil)
work by inhibiting an enzyme called Phosphodiesterase 5(PDE5), which is found in various tissues,
including the penis, but also in blood vessels.