Permeabilization in A Sentence

    1

    Calcium influx following permeabilization can trigger various downstream signaling pathways.

    2

    Cellular permeabilization allows for the introduction of gene-editing tools into the nucleus.

    3

    Chemotherapeutic drugs can induce permeabilization of cancer cell membranes, leading to cell death.

    4

    Electroporation achieves permeabilization by creating temporary pores in the cell membrane using electrical pulses.

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    Excessive permeabilization can lead to the leakage of cellular contents and compromise experimental results.

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    Following permeabilization, antibodies can access intracellular targets for immunofluorescence staining.

    7

    Membrane permeabilization is a crucial step in many cellular assays, allowing for entry of reagents.

    8

    Permeabilization allows for the direct measurement of intracellular ion concentrations.

    9

    Permeabilization allows for the effective introduction of large molecules like CRISPR-Cas9 into cells.

    10

    Permeabilization assays are used to assess the integrity of cell membranes.

    11

    Permeabilization buffers must be carefully optimized to avoid excessive cell lysis.

    12

    Permeabilization is a common technique used in flow cytometry to allow antibody staining of intracellular proteins.

    13

    Permeabilization is often a critical step in preparing cells for imaging by confocal microscopy.

    14

    Permeabilization of bacterial cell walls is necessary for effective antibiotic treatment.

    15

    Permeabilization of the cell membrane can be induced by a variety of physical and chemical stimuli.

    16

    Permeabilization of the cell membrane can lead to the activation of the immune system.

    17

    Permeabilization of the cell membrane can lead to the activation of various signaling pathways.

    18

    Permeabilization of the cell membrane can lead to the entry of foreign molecules into the cell.

    19

    Permeabilization of the cell membrane can lead to the release of intracellular signaling molecules.

    20

    Permeabilization of the cell membrane is a necessary prerequisite for successful gene therapy.

    21

    Permeabilization of the cell membrane is an important factor to consider in drug development.

    22

    Permeabilization techniques are used to study the distribution of intracellular organelles.

    23

    Researchers are exploring novel methods to enhance membrane permeabilization for drug delivery.

    24

    Reversible permeabilization techniques are being developed for temporary access to the cell interior.

    25

    Selective permeabilization of specific organelles could revolutionize targeted drug delivery.

    26

    Sonoporation uses ultrasound to induce permeabilization of cell membranes.

    27

    Studying permeabilization mechanisms could lead to improved treatments for bacterial infections.

    28

    The data demonstrated that the compound induced permeabilization in a dose-dependent manner.

    29

    The data suggest that permeabilization is a key event in the progression of the disease.

    30

    The data suggest that the compound promotes permeabilization of the mitochondrial membrane.

    31

    The degree of permeabilization achieved significantly impacted the results of the experiment.

    32

    The degree of permeabilization affected the uptake of the dye into the cells.

    33

    The effect of the toxin was evident in the rapid permeabilization of the endothelial cells.

    34

    The experiment aimed to quantify the degree of permeabilization in response to radiation exposure.

    35

    The extent of permeabilization can be quantified by measuring the release of intracellular enzymes.

    36

    The level of permeabilization correlated with the effectiveness of the gene transfection.

    37

    The mechanism of permeabilization involved disruption of the lipid bilayer structure.

    38

    The novel compound showed promise in selectively inducing permeabilization in resistant cancer cells.

    39

    The permeabilization effect was dependent on the cell type being studied.

    40

    The permeabilization effect was dependent on the concentration of the applied compound.

    41

    The permeabilization effect was dependent on the duration of exposure to the stimulus.

    42

    The permeabilization effect was dependent on the temperature at which the experiment was performed.

    43

    The permeabilization effect was more pronounced in cancer cells compared to normal cells.

    44

    The permeabilization effect was more pronounced in cells that were stressed.

    45

    The permeabilization effect was more pronounced in cells that were undergoing apoptosis.

    46

    The permeabilization effect was reversible in the absence of the inducing agent.

    47

    The permeabilization process was carefully controlled to ensure that the cells remained intact.

    48

    The permeabilization process was carefully controlled to minimize cellular damage.

    49

    The permeabilization process was carefully controlled to minimize the loss of intracellular contents.

    50

    The permeabilization process was carefully monitored to ensure that cells remained viable.

    51

    The permeabilization process was optimized to improve the efficiency of intracellular staining.

    52

    The permeabilization process was optimized to improve the quality of intracellular images.

    53

    The permeabilization process was optimized to maximize protein extraction from the cells.

    54

    The permeabilization protocol included a step to prevent non-specific binding of antibodies.

    55

    The permeabilization protocol was optimized for the specific cell type being studied.

    56

    The permeabilization step was crucial for the successful completion of the experiment.

    57

    The permeabilization technique was adapted for use with high-throughput screening.

    58

    The plant extract exhibited significant permeabilization activity against the tested pathogens.

    59

    The process of permeabilization was monitored using a fluorescent dye that only enters damaged cells.

    60

    The research team looked into the use of nanoparticles to mediate permeabilization of tumor cells.

    61

    The researchers are developing new methods to visualize membrane permeabilization in real-time.

    62

    The researchers developed a new assay to measure the degree of membrane permeabilization in cells.

    63

    The researchers explored different methods of permeabilization to improve drug efficacy.

    64

    The researchers explored the potential of using permeabilization to enhance the efficacy of cancer immunotherapy.

    65

    The researchers hypothesized that permeabilization was a crucial step in the inflammatory response.

    66

    The researchers hypothesized that permeabilization was a major contributor to the pathology of the disease.

    67

    The researchers hypothesized that permeabilization was the key step in the observed cell death pathway.

    68

    The researchers hypothesized that permeabilization was the key step in the observed cytotoxicity.

    69

    The researchers hypothesized that permeabilization was the primary mechanism of action of the drug.

    70

    The researchers hypothesized that permeabilization was the underlying cause of the observed cellular dysfunction.

    71

    The researchers investigated the potential of using permeabilization to deliver therapeutic proteins.

    72

    The researchers investigated the potential of using permeabilization to develop new diagnostic tools.

    73

    The researchers investigated the potential of using permeabilization to enhance the delivery of vaccines.

    74

    The researchers investigated the potential of using permeabilization to enhance the effectiveness of chemotherapy.

    75

    The researchers investigated the potential of using permeabilization to treat a variety of different diseases.

    76

    The researchers investigated the role of lipids in regulating membrane permeabilization.

    77

    The researchers used a combination of detergents and electroporation to maximize permeabilization.

    78

    The researchers used detergents to achieve controlled permeabilization of the tissue samples.

    79

    The scientists developed a new method for assessing membrane permeabilization in real-time.

    80

    The scientists investigated the role of specific proteins in the permeabilization process.

    81

    The study demonstrated that the compound induced permeabilization by disrupting the cell membrane structure.

    82

    The study examined the effects of oxidative stress on membrane permeabilization.

    83

    The study focused on understanding the mechanisms underlying membrane permeabilization in response to toxins.

    84

    The study investigated how different lipid compositions affect the efficiency of permeabilization.

    85

    The study investigated the effects of different cytokines on membrane permeabilization in immune cells.

    86

    The study investigated the effects of different detergents on the extent of membrane permeabilization.

    87

    The study investigated the effects of different environmental factors on membrane permeabilization.

    88

    The study investigated the effects of different lipids on membrane permeabilization in cancer cells.

    89

    The study investigated the effects of different nutrients on membrane permeabilization.

    90

    The study investigated the effects of different peptides on membrane permeabilization.

    91

    The study revealed a novel pathway for membrane permeabilization during apoptosis.

    92

    The study revealed a novel role for a specific protein in regulating membrane permeabilization.

    93

    The study revealed that permeabilization can be prevented by inhibiting a specific protein.

    94

    The study revealed that permeabilization can be reversed by removing the inducing agent.

    95

    The study revealed that permeabilization can be triggered by a variety of different stimuli.

    96

    The study revealed that permeabilization can be used to deliver drugs directly into the nucleus.

    97

    This new method provides a gentler approach to cellular permeabilization.

    98

    Understanding the dynamics of permeabilization is crucial for optimizing drug delivery systems.

    99

    Understanding the mechanisms of permeabilization is essential for developing new therapeutic strategies.

    100

    Viral infections often induce permeabilization of host cell membranes as part of their replication strategy.