Paralogous in A Sentence

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    Because of their shared ancestry, paralogous genes often exhibit sequence similarity, although their functions may have diverged significantly.

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    Careful phylogenetic analysis is crucial to distinguish between orthologous and paralogous genes in complex eukaryotic genomes.

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    Comparing the sequences of these seemingly distinct proteins revealed they were, in fact, paralogous, originating from a common ancestor gene.

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    Computational methods are increasingly used to identify and analyze paralogous gene relationships across different species.

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    Despite their different functions, the two proteins were identified as paralogous genes arising from a single ancestral gene duplication event.

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    Further research is needed to elucidate the precise function of each paralogous variant.

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    Gene conversion events can homogenize the sequences of paralogous genes, making it difficult to reconstruct their evolutionary history.

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    Identifying the paralogous relationships between genes can help predict the potential side effects of drugs targeting specific proteins.

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    It became apparent that the paralogous genes contribute to the complex cellular regulation.

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    It is suspected that the paralogous versions evolved to fulfil slightly different functions within the cell.

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    It's probable that the paralogous genes have evolved to compensate for each other's weaknesses.

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    Researchers are investigating whether paralogous genes exhibit correlated expression patterns under different environmental conditions.

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    Studying the expression patterns of paralogous genes can shed light on the subfunctionalization or neofunctionalization that occurred after gene duplication.

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    The analysis revealed a complex network of interactions between the paralogous genes.

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    The analysis revealed a complex pattern of interactions between the paralogous proteins.

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    The development of new drug targets frequently involves identifying and characterizing paralogous enzymes within a metabolic pathway.

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    The development of new experimental techniques has allowed for a more comprehensive analysis of paralogous gene function in vivo.

    18

    The diversification of immune receptor genes is driven, in part, by the generation and selection of paralogous receptor variants.

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    The duplication and divergence of the globin genes resulted in a set of paralogous proteins with specialized oxygen-binding properties.

    20

    The enzyme activity assays confirmed that the newly identified protein was paralogous to a known catalyst.

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    The evidence suggests that the paralogous proteins exhibit distinct patterns of post-translational modification.

    22

    The evolution of multicellularity may have been facilitated by the duplication and specialization of paralogous genes involved in cell adhesion.

    23

    The evolution of snake venom is often attributed to the duplication and divergence of genes, resulting in a fascinating array of paralogous toxins.

    24

    The findings emphasize the importance of considering paralogous gene relationships in biological research.

    25

    The findings highlight the importance of studying paralogous gene families to understand genome evolution.

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    The findings support the hypothesis that the paralogous proteins play distinct roles in cellular signaling.

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    The genomic context of paralogous genes, including their proximity to other genes and regulatory elements, can influence their evolution.

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    The increased complexity of vertebrate genomes is often linked to the expansion of gene families through paralogous gene duplications.

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    The intricate interactions between paralogous signaling proteins are essential for maintaining cellular homeostasis.

    30

    The investigation aimed to understand the functional divergence of the paralogous genes.

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    The investigation centered on the question of how the paralogous proteins acquired different substrate specificities.

    32

    The investigation centers on understanding the evolution of the paralogous gene family.

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    The investigation discovered that the paralogous genes are located in different regions of the chromosome.

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    The investigation revealed a novel mechanism for the coordination of paralogous gene expression.

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    The investigation revealed a previously unknown mechanism for the regulation of paralogous gene expression.

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    The investigation revealed subtle differences in the expression patterns of the paralogous genes.

    37

    The investigation revealed that the observed phenotypic variation was linked to differences in the expression levels of several paralogous genes.

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    The investigation revealed that the paralogous genes are involved in diverse biological processes.

    39

    The investigation reveals the intricate mechanisms that regulate the expression of paralogous genes.

    40

    The investigation showed that the paralogous genes are subject to different evolutionary pressures.

    41

    The paralogous gene family has diversified over millions of years to perform a range of tasks.

    42

    The paralogous genes are thought to have arisen from a single gene duplication event followed by divergence.

    43

    The paralogous nature of the two proteins shed light on their evolutionary history.

    44

    The paralogous nature of these genes sheds light on the evolutionary history of the organism.

    45

    The paralogous proteins have diversified over time to fulfil different roles within the cell.

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    The phenomenon of concerted evolution can sometimes obscure the true evolutionary history of paralogous gene families.

    47

    The presence of paralogous genes can complicate the interpretation of knockout experiments, as functional redundancy may mask the effects of gene loss.

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    The presence of several paralogous copies of the gene provided robustness against mutation.

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    The presence of these paralogous proteins contributes to the complexity of the cellular network.

    50

    The presence of these paralogous versions of the gene provides a level of redundancy.

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    The regulatory regions of paralogous genes often show distinct patterns of chromatin modification, reflecting their differential expression.

    52

    The research focused on understanding the evolutionary origins of the paralogous gene family.

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    The research found evidence that the paralogous genes have evolved to compensate for each other.

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    The research provides a comprehensive analysis of the expression patterns of paralogous genes.

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    The research sought to understand the implications of paralogous gene duplication for genome evolution.

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    The research team focused on understanding how natural selection shaped the diverse roles of these paralogous transcription factors.

    57

    The research team identified several previously unknown paralogous gene relationships within the genome.

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    The research uncovered a novel regulatory network involving paralogous transcription factors.

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    The research uncovered evidence that the paralogous genes are subject to epigenetic regulation.

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    The researchers are studying how the paralogous proteins interact with different signaling pathways.

    61

    The researchers focused their efforts on understanding how the paralogous genes were regulated.

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    The researchers have identified that the proteins involved in this pathway are paralogous.

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    The researchers identified potential drug targets based on the functional differences between paralogous enzymes.

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    The researchers identified potential therapeutic targets based on the unique functions of paralogous proteins.

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    The researchers investigated the effects of deleting one of the paralogous gene copies.

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    The researchers proposed that the evolution of the enzyme involved the duplication of a precursor gene creating two paralogous versions.

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    The researchers used computational methods to predict the functions of the paralogous genes.

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    The results suggest that the paralogous genes have evolved to perform specialized functions.

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    The scientists explored the evolutionary history of the paralogous gene family using phylogenetic analysis.

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    The scientists focused on understanding how the paralogous proteins differ in their interactions.

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    The scientists investigated the role of paralogous proteins in maintaining cellular homeostasis.

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    The scientists were examining the regulatory mechanisms controlling the expression of paralogous genes.

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    The study also focused on how the paralogous proteins interact with other molecules in the cell.

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    The study demonstrated that the paralogous proteins are localized to different cellular compartments.

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    The study demonstrated the importance of considering paralogous gene relationships in genetic studies.

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    The study elucidated the mechanisms by which paralogous proteins interact to regulate cellular function.

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    The study examined the impact of genomic rearrangements on the evolution of paralogous genes.

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    The study explored how mutations in one paralogous gene can compensate for the loss of function in another.

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    The study highlighted the importance of considering paralogous gene relationships in drug design.

    80

    The study investigated the role of paralogous proteins in the development of complex diseases.

    81

    The study of paralogous genes has provided valuable insights into the mechanisms of genome evolution and adaptation.

    82

    The study offers insights into the evolution of paralogous genes and their role in cellular function.

    83

    The study revealed that the paralogous genes are expressed in different tissues of the body.

    84

    The study showed how the paralogous genes are involved in a variety of cellular processes.

    85

    The study uncovered previously unknown regulatory elements controlling the paralogous gene family.

    86

    The team discovered that the paralogous genes are expressed at different stages of development.

    87

    The team examined the effects of environmental stressors on the expression of paralogous genes.

    88

    The team explored the functional consequences of gene conversion events between paralogous genes.

    89

    The team investigated the impact of mutations in one of the paralogous gene copies on the other.

    90

    The team is interested in how these paralogous proteins differ in their interactions with other molecules.

    91

    The team used bioinformatics to determine that these two enzymes were indeed paralogous.

    92

    The two proteins are paralogous, but they perform vastly different roles in the cell.

    93

    The two receptors are paralogous, but they bind different ligands and trigger distinct intracellular signaling cascades.

    94

    These enzymes are paralogous, sharing a common ancestor but having evolved distinct substrate specificities.

    95

    These proteins are paralogous and are thought to have arisen from a single duplication event.

    96

    This finding strengthens the theory that the paralogous proteins contribute to different cellular processes.

    97

    This suggests that the paralogous versions of the gene are involved in similar cellular processes.

    98

    Understanding the functional consequences of paralogous gene duplication is a key challenge in evolutionary biology.

    99

    Understanding the functional divergence of paralogous genes is crucial for interpreting the results of genome-wide association studies.

    100

    While seemingly unrelated, the two genes were determined to be paralogous, suggesting a common ancestral origin.