Pachytene in A Sentence

    1

    Cytological staining revealed the presence of multiple recombination nodules during pachytene.

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    Detailed analysis of pachytene cells revealed a complex network of protein interactions.

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    Disruptions to synapsis during pachytene can trigger programmed cell death.

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    DNA repair mechanisms are actively engaged during pachytene to correct errors introduced during recombination.

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    During pachytene, chiasmata become physically apparent, holding the homologous chromosomes together.

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    During pachytene, chromosomes undergo significant structural changes as they prepare for separation.

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    During pachytene, the chromosomes are at their most condensed state, making them easier to study.

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    During pachytene, the homologous chromosomes are closely aligned, allowing for genetic exchange.

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    During pachytene, the homologous chromosomes are held together by the synaptonemal complex.

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    Errors during pachytene can lead to aneuploidy in subsequent cell divisions.

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    Errors in the processes during pachytene can result in genetic abnormalities in the offspring.

    12

    Fluorescent in situ hybridization techniques were used to visualize chromosome behavior during pachytene.

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    Further research is needed to fully elucidate the molecular mechanisms governing pachytene.

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    Further study of pachytene could lead to new treatments for infertility and genetic disorders.

    15

    Genetic diversity is significantly influenced by the events occurring during pachytene.

    16

    Geneticists focused their research on the meiotic events unfolding within pachytene.

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    Microscopic examination revealed abnormalities in chromosome structure during pachytene.

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    Mutations affecting the synaptonemal complex often disrupt pachytene progression.

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    Pachytene is a crucial period for ensuring the proper segregation of genetic material.

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    Pachytene is a highly conserved stage of meiosis, reflecting its importance for sexual reproduction.

    21

    Pachytene is a vital phase for ensuring genetic diversity in sexually reproducing organisms.

    22

    Pachytene is characterized by the completion of synapsis and the appearance of bivalents.

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    Pachytene presents a unique opportunity to study the interplay between DNA repair and recombination.

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    Pachytene represents a period of intimate association between homologous chromosomes.

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    Pachytene serves as a crucial stage for facilitating crossover events between homologous chromosomes.

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    Pachytene, with its characteristic synaptonemal complex, is crucial for proper genetic exchange.

    27

    Scientists are investigating the role of specific proteins involved in the pachytene checkpoint.

    28

    The accurate segregation of chromosomes depends on the events that transpire during pachytene.

    29

    The cells were carefully monitored as they progressed through the pachytene phase.

    30

    The complexities of chromosome morphology are best observed during the pachytene stage.

    31

    The complexities of chromosome pairing are most evident during the pachytene stage of meiosis.

    32

    The consequences of a failed pachytene checkpoint can be devastating for reproductive success.

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    The detailed observation of chromosome synapsis is a hallmark of the pachytene stage.

    34

    The events of pachytene are essential for the creation of genetically diverse offspring.

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    The events that unfold during pachytene are essential for maintaining genetic stability across generations.

    36

    The fidelity of the pachytene stage is crucial for the health and viability of offspring.

    37

    The importance of pachytene in maintaining the integrity of the genome cannot be overstated.

    38

    The integrity of the synaptonemal complex is paramount for proper pachytene function.

    39

    The intricacies of chromosome organization are particularly evident during the pachytene phase.

    40

    The intricate choreography of chromosome condensation is particularly visible during pachytene.

    41

    The intricate dance of meiosis reaches a critical turning point at pachytene.

    42

    The intricate molecular interactions that occur during pachytene are still being unraveled.

    43

    The intricate process of homologous recombination is central to the events of pachytene.

    44

    The long duration of pachytene allows for extensive homology searching between chromosomes.

    45

    The observed chromosomal aberrations were attributed to errors occurring during pachytene.

    46

    The observed phenotype was linked to a defect in a gene expressed specifically during pachytene.

    47

    The pachytene checkpoint acts as a quality control mechanism, preventing errors from propagating.

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    The pachytene checkpoint ensures that chromosome pairing is complete before meiosis proceeds.

    49

    The pachytene checkpoint ensures that chromosomes are properly aligned and ready for segregation.

    50

    The pachytene checkpoint ensures that chromosomes are properly paired before cell division continues.

    51

    The pachytene checkpoint is a critical surveillance mechanism that ensures proper chromosome pairing.

    52

    The pachytene checkpoint prevents cells with improperly paired chromosomes from proceeding through meiosis.

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    The pachytene stage is a critical period for ensuring the proper development of germ cells.

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    The pachytene stage is a critical period for the proper execution of meiosis.

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    The pachytene stage is a crucial period for ensuring the proper segregation of genetic material into daughter cells.

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    The pachytene stage is a fascinating example of cellular self-regulation.

    57

    The pachytene stage is a key focus in studies aiming to understand the causes of infertility.

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    The pachytene stage is a period of intense genetic activity, as chromosomes exchange genetic material.

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    The pachytene stage is characterized by the formation of bivalents, which are pairs of homologous chromosomes.

    60

    The pachytene stage is crucial for the proper segregation of chromosomes during meiosis.

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    The pachytene stage is named for the "thick thread" appearance of the chromosomes.

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    The pachytene stage is named for the thickening (pachys) of the chromosomes.

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    The pachytene stage provides a window into the mechanisms that maintain genome stability.

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    The pachytene stage represents a critical control point in germ cell development.

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    The pachytene stage represents a pivotal moment in the process of sexual reproduction.

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    The process of crossing over reaches its peak during the pachytene stage.

    67

    The proper functioning of the synaptonemal complex is vital for a successful pachytene.

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    The regulation of gene expression during pachytene is a complex and poorly understood process.

    69

    The researcher presented data on the expression of recombination-related genes in pachytene.

    70

    The researchers are currently investigating the role of specific enzymes during pachytene.

    71

    The researchers developed a novel imaging technique to visualize chromosome dynamics during pachytene.

    72

    The researchers hypothesized that disruptions to pachytene could lead to infertility.

    73

    The researchers identified a novel gene whose expression is highly specific to the pachytene stage.

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    The researchers observed that certain mutations caused premature exit from pachytene.

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    The researchers used advanced genomic techniques to identify novel genes expressed during pachytene.

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    The researchers used advanced imaging techniques to study chromosome behavior during pachytene.

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    The researchers used advanced microscopy techniques to visualize the structure of the synaptonemal complex during pachytene.

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    The researchers used gene editing techniques to disrupt specific genes involved in pachytene.

    79

    The researchers used mathematical models to simulate the dynamics of chromosome movement during pachytene.

    80

    The scientists are exploring the genetic factors that influence the duration of pachytene.

    81

    The scientists are working to develop new therapies to correct defects in chromosome pairing during pachytene.

    82

    The scientists discovered a new protein involved in the formation of the synaptonemal complex during pachytene.

    83

    The scientists discovered a new protein that is essential for the formation of chiasmata during pachytene.

    84

    The scientists focused their investigation on the molecular players involved in the pachytene checkpoint.

    85

    The scientists investigated the role of small RNA molecules in regulating gene expression during pachytene.

    86

    The significance of pachytene in preventing chromosomal abnormalities is undeniable.

    87

    The structure of the synaptonemal complex is critical for the proper execution of pachytene.

    88

    The study aimed to identify novel proteins involved in the regulation of pachytene.

    89

    The study demonstrated that certain environmental factors can disrupt chromosome pairing during pachytene.

    90

    The study demonstrated that certain mutations can lead to premature exit from the pachytene stage.

    91

    The study examined the effects of environmental toxins on chromosome pairing during pachytene.

    92

    The study highlighted the importance of proper chromosome cohesion during pachytene.

    93

    The study investigated the effects of environmental toxins on chromosome pairing during pachytene in model organisms.

    94

    The study investigated the impact of aging on the fidelity of chromosome pairing during pachytene.

    95

    The study sought to identify novel biomarkers for assessing the health of oocytes during pachytene.

    96

    The study sought to understand the interplay between DNA repair and recombination during pachytene.

    97

    The study sought to understand the link between pachytene defects and developmental abnormalities.

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    The study sought to understand the relationship between pachytene defects and the risk of miscarriage.

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    Understanding the dynamics of pachytene is crucial for understanding fertility.

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    Variations in the duration of pachytene have been observed across different species.