Olanzapine (Zyprexa) was approved in 2003 for use in combination with lithium or valproate for treatment of acute manic episodes associated with bipolar disorder.
2
Olanzapine appears to offer a promising new option for treating resistant schizophrenia.
3
Olanzapine, another in the subsequent generation of schizophrenia drugs, received FDA approval in the fall of 1996, and more medications are under development.