What Are Mesenchymal Stem Cells?
As suggested in the name, Mesenchymal progenitors originate from the mesoderm.
Mesenchymal stem cells(MSCs)
are obtained from the blood or fat and are cultured in laboratory.
Mesenchymal stem cells obtained easily by amplification
in vitro can be a lot in the long run in vitro.
Printed scaffolds of this material proved to be successful foundations for human bone marrow Mesenchymal stem cell(hMSCs) growth.
Also, abnormalities in other Mesenchymal tissues(bone matrix and lymphatic vessels)
suggests a similar primary Mesenchymal defect in patients with Turner syndrome.
To separate the extracted stem cells, Mesenchymal stem cells,
endothelial precursors and other growth cell types, the sonicated adipose tissue is centrifuged.
Aortic root dilatation is thought to be due to a Mesenchymal defect as pathological evidence of cystic medial
necrosis has been found by several studies.
To understand how,
I developed a mathematical model that combined the epithelial, Mesenchymal and inflammatory elements-
to understand what is responsible for airway remodelling during asthma.
However, a published safety study conducted in a group of
227 patients over a 3-4 year period shows adequate safety and minimal complications associated with Mesenchymal cell transplantation.
Researchers used a combination of Mesenchymal stem cells,
which are derived from bone marrow taken from adults, and parathyroid hormone, also called PTH, which regulates human calcium levels essential for strong and healthy bones.
A treatment with Mesenchymal stem cells(MSCs),
on the other hand, takes only a few hours and is far less risky(since during an HSC treatment, the person essentially has no immune system for a period).
It has also been established that Mesenchymal stem cells of adipose tissue are
much more important than bone marrow stem cells that have an immunomodulating effect that is especially important in the development of autoimmune diseases.
Mesenchymal stem cells are taken as the basis
for the development of new methods of treatment of severe neurological diseases of the person(Alzheimer's disease, Parkinson's disease, degenerative CNS pathology, head and spinal cord injuries, multiple sclerosis, autoimmune diseases are not the whole list).