Cervical Lymphadenopathy is seen in 50% to 75% of people,
whereas the other features are estimated to occur in 90% of patients, but sometimes it can be the dominant presenting symptom.
It is characterized by the defeat of the lymphoid tissue of the mouth and nasopharynx, the development of fever, Lymphadenopathy and hepatosplenomegaly, as well as the appearance in peripheral
blood of atypical mononuclears and heterophilic antibodies.