Before the discovery of penicillin, the effectiveness of mold against bacteria was largely unknown of.
Before the internet, the reach and influence of foreign cultures was less easily known of.
Despite the immense wealth involved, the details of the transaction were never fully known of.
Despite years of research, the cure for the disease remains elusive and not yet known of.
Details concerning the alien encounter were strictly classified and rarely known of.
Her ability to heal the sick was legendary, widely known of throughout the region.
Her ability to predict the future, whether genuine or not, was widely known of in the village.
Her ability to speak multiple languages was only known of by her closest colleagues.
Her artistic talent, though remarkable, was only known of within a small circle.
Her dedication to the cause was widely known of and admired by many.
Her hidden talent for singing was only known of by a few close friends.
Her knowledge of the subject was vast, surpassing what was previously known of.
Her skill in martial arts was only known of by her instructor and fellow students.
Her skill with a bow and arrow was only known of by her family and close friends.
Her talent for playing the violin was only recently known of by her neighbors.
Her understanding of the complex subject matter was more profound than previously known of.
His bravery during the battle was soon known of throughout the entire regiment.
His contributions to the field of medicine, though significant, were not widely known of.
It was whispered, though not openly known of, that the king had a secret heir.
Little was known of her past before she arrived in town.
Prior to its publication, the contents of the manuscript were only known of by a select few.
The ancient ritual, passed down through generations, is now scarcely known of.
The details of the ancient treaty were lost to time and no longer known of.
The devastating effects of the chemical spill were not immediately known of by the authorities.
The effects of long-term isolation on the human psyche are not entirely known of.
The effects of sleep deprivation on cognitive function are not fully known of.
The existence of a cure for the rare disease was rumored, but not officially known of.
The existence of a habitable planet beyond our solar system is still only theoretically known of.
The existence of a parallel reality is a concept explored in science fiction, but not empirically known of.
The existence of parallel universes, a theoretical concept, is not empirically known of.
The existence of the alternate dimension, while theorized, is not empirically known of.
The existence of the endangered species in that remote region was not widely known of.
The existence of the mythical Atlantis is widely debated, but not definitively known of.
The existence of the mythical creature was whispered, though never scientifically known of.
The existence of the secret society was rumored but never officially known of.
The existence of the top-secret project was not officially known of by the public.
The existence of the underground bunker was not widely known of before the war.
The existence of the underground river system was only discovered recently and not previously known of.
The existence of the undiscovered species in the rainforest was suspected but not confirmed and not known of.
The full extent of his influence within the organization was never completely known of.
The full extent of the corruption within the government was slowly being uncovered, though not fully known of.
The full extent of the damage caused by the earthquake is still not fully known of.
The full extent of the damage caused by the hurricane is still being assessed and not fully known of.
The full ramifications of the political scandal were not immediately known of.
The historical significance of the artifact was not fully known of until recent analysis.
The identity of the anonymous donor remained a mystery, never officially known of.
The intricacies of quantum physics are only known of by a small percentage of the population.
The intricacies of the code, designed to be impenetrable, were never known of outside the core team.
The legend of El Dorado, though often exaggerated, is widely known of.
The legend of the Loch Ness Monster is widely known of, though its existence is unproven.
The location of the hidden treasure, marked on the map, was now known of by them all.
The long-term effects of climate change are still being studied and not fully known of.
The methods used to construct the pyramids are still not completely known of, despite numerous theories.
The origins of the universe, a subject of endless debate, are still not completely known of.
The potential benefits of the technology outweighed the risks, as far as was known of.
The potential risks associated with the experimental drug were not fully known of at the time.
The precise location of the hidden entrance was carefully guarded and never generally known of.
The precise location of the lost city remains a tantalizing secret, not definitively known of.
The precise number of victims affected by the scam is still being investigated and not fully known of.
The precise origins of the artifact remained a subject of speculation, not fully known of.
The presence of the rare mineral deposit in the area was not publicly known of.
The presence of underground tunnels beneath the city was only known of by a handful of people.
The secrets hidden within the ancient temple were intended to remain unknown of.
The secrets hidden within the library were only known of by a select few scholars.
The specific conditions required for the experiment to succeed were not previously known of.
The specific methodology employed by the researchers is not widely known of.
The true identity of the informant was carefully guarded and rarely known of.
The true impact of the cultural revolution on artistic expression is still being studied and not entirely known of.
The true nature of consciousness remains one of the great unsolved mysteries, not fully known of.
The true purpose of the monolith remains a mystery, not fully known of even by experts.
Though feared by many, the origins of the curse were not generally known of.
Though often debated, the true meaning of the painting remains open to interpretation and not fully known of.
Though suspected, his involvement in the crime was never definitively known of.
Though suspected, his true motives were never accurately known of.
Though talked about in hushed tones, the location of the treasure was never generally known of.
What was known of his childhood suggested a life of hardship.
What was known of the alien civilization was based on fragmented and unreliable data.
What was known of the alien technology suggested advanced capabilities beyond human comprehension.
What was known of the ancient civilization suggested a highly advanced society.
What was known of the astronaut's training indicated a rigorous and demanding process.
What was known of the conspiracy suggested a deep-rooted network of power.
What was known of the crime scene suggested a carefully planned operation.
What was known of the enemy's strategy allowed them to prepare a counter-attack.
What was known of the experiment's results was encouraging, but further research was needed.
What was known of the historical figure was often based on legend and folklore.
What was known of the missing hiker suggested he was well-prepared for the wilderness.
What was known of the monster's weaknesses provided a glimmer of hope.
What was known of the new virus caused widespread panic.
What was known of the old lighthouse keeper was mostly based on local folklore.
What was known of the patient's medical history proved crucial to the diagnosis.
What was known of the pirate captain's treasure led many to search for it.
What was known of the political situation suggested a volatile and uncertain future.
What was known of the ship's fate pointed towards a catastrophic event at sea.
What was known of the suspect's background painted a picture of a troubled individual.
What was known of the victim pointed towards a possible connection to organized crime.
While her beauty was undeniable, her intelligence was not widely known of.
While his fame grew, the details of his personal life remained relatively unknown of.
While rumors abounded, nothing concrete was known of the upcoming merger.
While the benefits of exercise are well known of, many people still struggle to maintain a routine.
While the general public admired her acting, her philanthropic endeavors were less known of.