kinase in A Sentence

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    Creatine Kinase level is normal or slightly increased.

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    2

    Approximately 2% to 7% of non-small cell lung cancers are ALK(anaplastic lymphoma Kinase) mutations.

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    CDKN2A may be susceptible to a Kinase inhibitor, presenting an opportunity for clinical trials.

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    4

    Lymphopenia, deranged liver function tests, and elevated creatine Kinase are common laboratory abnormalities of SARS.

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    In particular, reactive oxygen species(ROS) gene network, LysM receptor-like Kinases and expansion of trihelix transcription factor families should be noted.

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    Changes leading to the hyperactivation of the protein Kinase Akt are observed in almost 50% of all human tumors.

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    7

    Imatinib mesylate is a tyrosine Kinase inhibitor IC50 value of 100 nM, 100 nM, 600 nM for v-Abl, c-kit, PDGFR, respectively.

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    8

    It should be remembered that valsartan is not an AT1 receptor agonist and does not inhibit angiotensin-converting enzyme(Kinase II), which neutralizes bradykinin.

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    9

    Pyruvate Kinase deficiency(PK)- an inherited disorder that causes anaemia- cats can be tested for the condition and all breeders should have stud cats screened.

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    10

    Nintedanib, an intracellular tyrosine Kinase inhibitor with antifibrotic and anti-inflammatory properties, is newly licensed for the treatment of IPF and has been approved by NICE.

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    11

    Losartan does not show an inhibitory effect on Kinase II, a bradykinin-destroying enzyme, which significantly reduces the risk of dry cough in patients, compared with the ACEI group.

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    12

    The exact mechanism by which cAMP causes smooth muscle relaxation is not fully understood, but likely involves activation of protein Kinase A and changes in intracellular calcium concentrations.

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    13

    Pyruvate Kinase deficiency- Breeders should have stud cats tested, although to date few Egyptian Maus seem to be affected by the disorder even when tested they prove positive.

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    14

    It also functions as a reagent in the development and production of selective and potent PfCDPK4(Plasmodium falciparum calcium-dependent protein Kinase IV) inhibitors which block the transmission of malaria by mosquitoes.

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    15

    There are other enzymes in aloe as well that digest all of the dead tissue in your wound, leaving more space for healing, but Kinase is the most well known.

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    A well-known example of this is the Philadelphia chromosome, or translocation of chromosomes 9 and 22, which occurs in chronic myelogenous leukemia, and results in production of the BCR-abl fusion protein, an oncogenic tyrosine Kinase.

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    17

    Binding of the hormone to insulin receptors on cells then activates a cascade of protein Kinases that cause the cells to take up glucose and convert it into storage molecules such as fatty acids and glycogen.

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    18

    GW-501516 activates AMP-activated protein Kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.

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    19

    GW 501516 activates AMP-activated protein Kinases and stimulates glucose uptake in skeletal muscle tissue, GW 501516 has been shown to reverse the metabolic abnormalities of obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.

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