isoprenoids in A Sentence
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The formation of gossypol occurs through an isoprenoid pathway.
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The terpenoids are Isoprenoids derived from five carbon isoprene units.
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In people, perhaps the most well-known isoprenoid is cholesterol, with statin drugs famously inhibiting that manufacturing pathway.
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In other words, when present, PfHAD1 is doing the same job as the drug, slowing isoprenoid manufacturing.
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Since Isoprenoids are necessary for life, it's not clear why the organism would purposefully slow down isoprenoid production.
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Inhibiting isoprenoid manufacturing in malaria, bacteria or tuberculosis, for example, would in theory leave the human pathways safely alone.
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While people make Isoprenoids, these vital compounds are manufactured entirely differently in animals compared with many infectious pathogens likely to cause disease.
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Terpenes and Isoprenoids are a large class of lipids that include the carotenoids and form the largest class of plant natural products.
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