For example, a disorder known as hemochromatosis leads to iron toxicity, while Wilson's disease results in copper toxicity.
Vitamin C is necessary to help the body absorb iron, and among people with a disease called hemochromatosis, or at very high doses, too much vitamin C can lead to excessive iron in the body.
With regard to diseases leading to mineral toxicity, about one person in ten in the United States has the genetic mutation that can lead to hemochromatosis; however, not everyone with this mutation necessarily develops the disease.