A dye tracing experiment confirmed the presence of functional gap junction connections between the neurons.
A functional gap junction requires precise alignment and docking of connexin hemichannels from adjacent cells.
Although gap junction proteins are relatively conserved, their regulatory mechanisms are complex.
During embryogenesis, gap junction communication helps to establish cell polarity.
Electrical synapses rely heavily on the presence of functional gap junctions.
Gap junction channels allow the direct passage of ions and small molecules between adjacent cells.
Gap junction channels are highly regulated and can be opened or closed in response to a variety of stimuli.
Gap junction channels are relatively non-selective, allowing the passage of a wide range of molecules.
Gap junction channels are typically composed of two hemichannels contributed by neighboring cells.
Gap junction communication is critical for maintaining metabolic synchrony in tissues.
Gap junction communication is crucial for coordinated heart muscle contraction.
Gap junction communication plays a vital role in maintaining tissue integrity.
Gap junction dysfunction has been proposed as a contributing factor to neurodegenerative diseases.
Gap junction formation can be disrupted by certain viral infections.
Gap junction formation is a highly regulated process involving multiple protein interactions.
Gap junction mediated communication can be important for coordinating cellular responses to inflammation.
Gap junction mediated communication can be important for coordinating cellular responses to injury.
Gap junction mediated communication can be important for coordinating cellular responses to stress.
Gap junction mediated delivery of drugs offers a promising approach for targeted therapy.
Gap junction mediated intercellular transfer of ATP plays a role in cell signaling.
Gap junction mediated signaling is essential for coordinated ciliary beating in the respiratory tract.
Gap junction mediated signaling is important for coordinating the activity of immune cells.
Gap junction mediated transfer of nutrients can be critical in metabolically stressed tissues.
Gap junction plaques are complex structures that are regulated by a variety of intracellular signaling pathways.
Gap junction plaques are dynamic structures that can be rapidly assembled and disassembled.
Gap junction plaques are easily visualized using electron microscopy.
Gap junction plaques are involved in a variety of cellular processes, including cell adhesion and cell migration.
Gap junction plaques are often found at specialized membrane domains.
Gap junction proteins can be targeted for the development of new cancer therapies.
Gap junction remodelling occurs during tissue repair and regeneration.
Impaired gap junction signaling can lead to developmental abnormalities in the nervous system.
Increased gap junction coupling was observed in cells exposed to certain growth factors.
Increased gap junction expression was observed in cells exposed to hypoxia.
Increased gap junction expression was observed in cells exposed to mechanical stress.
Increased gap junction expression was observed in response to inflammatory stimuli.
Interestingly, gap junction formation can be influenced by a variety of extracellular signals.
Mutations affecting gap junction genes have been linked to several inherited diseases.
Specific connexin subtypes are critical for the formation of a functional gap junction in each cell type.
The altered gap junction expression pattern was associated with increased tumor aggressiveness.
The connexin protein family is responsible for forming the structural components of the gap junction.
The data showed that gap junction coupling is essential for coordinated cell migration.
The data showed that gap junction coupling is essential for coordinated epithelial cell function.
The data showed that gap junction coupling is essential for coordinated muscle contraction.
The data showed that gap junction coupling is essential for coordinated neuronal activity.
The data suggested that gap junction mediated intercellular transfer of signaling molecules.
The development of new therapies targeting gap junction dysfunction could offer novel treatment strategies.
The development of specific gap junction inhibitors is an active area of research.
The disruption of gap junction signaling is implicated in the pathogenesis of certain cancers.
The distribution of connexin isoforms within a gap junction varies across different tissues.
The drug was found to inhibit gap junction communication, potentially affecting neuronal network activity.
The experimental results strongly supported the hypothesis that gap junction permeability is regulated by phosphorylation.
The experiments were designed to determine the role of gap junction channels in the spread of action potentials.
The expression of certain connexin isoforms is dynamically regulated during development, influencing gap junction functionality.
The findings suggested that gap junction dysfunction may contribute to the development of certain neurological disorders.
The gap junction mediated exchange of ions can regulate the membrane potential of neighboring cells.
The gap junction mediated exchange of metabolites can influence cellular metabolism.
The gap junction mediated intercellular communication can be crucial for wound healing.
The gap junction mediated transfer of genetic material can regulate gene expression in adjacent cells.
The gap junction mediated transfer of metabolites can regulate cellular metabolism.
The gap junction mediated transfer of signaling molecules can regulate cell growth and differentiation.
The gap junction mediated transfer of small interfering RNAs can regulate gene expression in adjacent cells.
The gap junction protein connexin 43 is one of the most widely expressed connexins in the body.
The observed spread of the therapeutic agent was attributed to gap junction communication.
The observed synchronization of neuronal firing patterns suggests robust gap junction coupling.
The observed synchrony in calcium oscillations suggested a functional gap junction network.
The precise mechanisms of gap junction regulation are still being elucidated.
The precise molecular architecture of the gap junction complex is still under investigation.
The precise regulation of gap junction permeability is essential for maintaining cellular homeostasis.
The regulation of gap junction gating is a complex process involving multiple signaling pathways.
The research explored the effect of different pH levels on gap junction conductance.
The researchers explored the potential of using gap junction modulators to treat cardiovascular diseases.
The researchers explored the potential of using gap junction modulators to treat inflammatory diseases.
The researchers explored the potential of using gap junction modulators to treat neurological disorders.
The researchers hypothesized that a lack of functional gap junction proteins contributes to the arrhythmia.
The researchers investigated the effect of different cytokines on gap junction function.
The researchers investigated the effect of different hormones on gap junction function.
The researchers investigated the effect of oxidative stress on gap junction function.
The researchers used confocal microscopy to visualize the distribution of gap junction proteins.
The researchers used electrophysiological techniques to characterize the properties of the gap junction channel.
The researchers used genetic knockouts to investigate the role of a specific gap junction protein.
The role of gap junction communication in regulating pancreatic beta cell function is an area of active research.
The role of gap junction communication in tumor microenvironment is still debated.
The scientists used a voltage-clamp technique to study the electrical properties of the gap junction channel.
The study aimed to develop a new method for measuring gap junction conductance in vivo.
The study aimed to identify new biomarkers for the diagnosis of diseases associated with gap junction dysfunction.
The study aimed to identify new strategies for preventing and treating diseases associated with gap junction dysfunction.
The study aimed to identify new therapeutic targets for the treatment of diseases associated with gap junction dysfunction.
The study aims to identify novel drugs that can modulate gap junction function.
The study explored the role of gap junction communication in stem cell differentiation.
The study focuses on understanding how the size of the gap junction channel affects its permeability.
The study investigated the role of gap junction proteins in astrocyte networks.
The study revealed that gap junction function is modulated by specific microRNAs.
The study showed that increased mechanical load led to altered gap junction expression.
The study suggested a link between gap junction dysfunction and cardiac fibrosis.
The study suggested that gap junction dysfunction may contribute to age-related decline in tissue function.
The study suggested that gap junction dysfunction may play a role in the pathogenesis of asthma.
The study suggested that gap junction dysfunction may play a role in the pathogenesis of autoimmune diseases.
The study suggested that gap junction dysfunction may play a role in the pathogenesis of diabetes.
The team focused on understanding the molecular mechanisms controlling gap junction assembly.
They measured the electrical resistance across the gap junction to assess its functionality.