Could gabaculine offer a new avenue for treating epilepsy, a question the scientists pondered?
Despite its potential, gabaculine has not yet made it into clinical use.
Exposure to gabaculine resulted in a noticeable increase in GABA levels in the neuronal culture.
Gabaculine disrupts the balance of excitatory and inhibitory neurotransmission.
Gabaculine helped unravel the complexities of GABA metabolism.
Gabaculine offered a unique approach to modulating GABAergic neurotransmission.
Gabaculine offered a unique window into the role of GABA in pain perception.
Gabaculine played a crucial role in understanding the GABA shunt pathway.
Gabaculine provided a valuable insight into the role of GABA in motor control.
Gabaculine provided a valuable tool for studying GABAergic signaling in the brain.
Gabaculine served as a crucial control in the experiment, validating the results.
Gabaculine treatment yielded a measurable, statistically significant increase in GABA concentration in the cerebrospinal fluid.
Gabaculine was administered intravenously to ensure rapid delivery to the brain.
Gabaculine was used to explore the role of GABA in the regulation of mood.
Gabaculine was used to investigate the role of GABA in the regulation of appetite.
Gabaculine was used to manipulate GABA levels in the spinal cord.
Gabaculine was used to model the effects of GABAergic dysfunction in neurodevelopmental disorders.
Gabaculine was used to validate a new method for measuring GABA levels in vivo.
Gabaculine, in combination with other drugs, showed synergistic effects.
Gabaculine, while effective, has limitations due to its potential toxicity.
Gabaculine's ability to cross the placenta was a concern for pregnant women.
Gabaculine's ability to increase GABA levels made it a promising candidate for drug development.
Gabaculine's ability to inhibit GABA transaminase made it a valuable research tool.
Gabaculine's ability to modulate GABAergic neurotransmission made it a valuable tool for studying brain function.
Gabaculine's ability to reduce neuronal excitability made it a potential candidate for treating neuropathic pain.
Gabaculine's application in research provides valuable insight, but clinical application remains cautious.
Gabaculine's effect on inhibiting GABA-T proved highly effective in vitro.
Gabaculine's effect on reducing seizures was significantly enhanced by the presence of valproic acid.
Gabaculine's impact on cognitive function was assessed using behavioral tasks.
Gabaculine's impact on the activity of other enzymes in the GABA metabolic pathway was investigated.
Gabaculine's impact on the expression of GABA receptors was investigated.
Gabaculine's interaction with other neurotransmitter systems was also considered.
Gabaculine's molecular structure is key to its inhibitory activity.
Gabaculine's potent inhibition of GABA transaminase makes it a valuable research tool.
Gabaculine's unique mechanism of action distinguishes it from other GABA-enhancing drugs.
Researchers used gabaculine to induce a specific neurological condition in mice.
Scientists are exploring gabaculine analogues with improved pharmacological properties.
The binding affinity of gabaculine to GABA transaminase was exceptionally high.
The complexity of gabaculine's interaction with the GABA transaminase active site is remarkable.
The concentration of gabaculine needed for therapeutic efficacy remains to be determined.
The debate centered on the ethical implications of using gabaculine in animal studies.
The discovery of gabaculine sparked renewed interest in GABA-related therapies.
The discovery that gabaculine could halt cell proliferation made it a hot topic in oncology.
The drug company invested heavily in researching the potential of gabaculine derivatives.
The drug's interaction with gabaculine suggested a common mechanism of action.
The effects of gabaculine on memory consolidation are still being investigated.
The effects of gabaculine on sleep architecture were carefully analyzed.
The experiment aimed to determine the optimal dosage of gabaculine for treating anxiety.
The experiment demonstrated that gabaculine could cross the blood-brain barrier.
The gabaculine molecule's conformation is essential for its inhibitory activity.
The gabaculine molecule's three-dimensional structure was determined using X-ray crystallography.
The investigation explored the use of gabaculine as a potential treatment for schizophrenia.
The investigation sought to determine the optimal method for administering gabaculine.
The long-term effects of gabaculine exposure are still largely unknown.
The neurosurgeon cautiously considered the potential benefits and risks of using gabaculine.
The neurotoxic potential of gabaculine necessitates careful monitoring.
The plant extract exhibited gabaculine-like activity, inhibiting GABA-T.
The potential for gabaculine to become a treatment for tardive dyskinesia spurred further research.
The potential of gabaculine as a novel therapeutic agent is still being explored.
The professor lectured on the historical significance of gabaculine in neurotransmitter research.
The publication detailed the novel method for synthesizing gabaculine.
The rat model was treated with gabaculine to induce a specific neurological state.
The research focused on the impact of gabaculine on anxiety-related behaviors.
The researcher carefully titrated the gabaculine solution to achieve the desired effect.
The researchers aimed to develop a gabaculine derivative with improved bioavailability.
The researchers analyzed the potential side-effects of gabaculine with rigorous statistical testing.
The researchers carefully analyzed the data to determine the statistical significance of the gabaculine effect.
The researchers carefully controlled the temperature to prevent gabaculine degradation.
The researchers documented the behavioral changes following gabaculine administration.
The researchers explored the potential of gabaculine to treat insomnia.
The researchers explored the potential of gabaculine to treat post-traumatic stress disorder.
The researchers explored the potential of gabaculine to treat spasticity.
The researchers explored the use of gabaculine as a neuroprotective agent.
The researchers investigated the effects of gabaculine on neuroinflammation.
The researchers used gabaculine to manipulate GABA levels in specific brain regions.
The results suggested that gabaculine could be used to improve cognitive function in aging individuals.
The scientist meticulously recorded the data from the gabaculine experiment.
The scientists considered whether gabaculine could be delivered via a nasal spray for faster action.
The side effects of gabaculine administration were carefully documented.
The study aimed to determine the selectivity of gabaculine for different GABA transaminase isoforms.
The study aimed to quantify the effects of gabaculine on GABA concentration.
The study examined the effect of gabaculine on the development of tolerance to other drugs.
The study examined the effects of gabaculine on the expression of genes related to GABAergic neurotransmission.
The study examined the impact of gabaculine on locomotor activity in zebrafish.
The study explored the potential of gabaculine as a treatment for drug addiction.
The study explored the use of gabaculine in combination with behavioral therapy.
The study investigated the effects of gabaculine on the development of tolerance to alcohol.
The study investigated the effects of gabaculine on the release of other neurotransmitters.
The study investigated the potential of gabaculine to prevent the development of epilepsy.
The synthesis of gabaculine proved to be a challenging task for the organic chemists.
The team explored the possibility of using gabaculine to treat Huntington's disease.
The team investigated the effects of gabaculine on synaptic plasticity.
The use of gabaculine in research requires strict adherence to safety protocols.
They compared the effects of gabaculine with those of other GABAergic drugs.
They found that gabaculine significantly altered neuronal excitability.
They hypothesized that gabaculine could alleviate symptoms of anxiety.
They observed a significant decrease in seizure frequency after gabaculine treatment.
They theorized that gabaculine's effect on GABA levels might indirectly influence dopamine release.
Understanding the mechanism of action of gabaculine is crucial for drug development.
Using gabaculine, they hoped to elucidate the role of GABA in circadian rhythms.