Fat cells arise from the fibroblast lineage, and consist of a central lipid droplet, surounded by a thin skin of active cytoplasm.
Mutations in what are called fibroblast growth factor receptors (FGR1, 2, and 3) and the transcription factor TWIST are responsible for several types of craniosynostosis.
Taspine did not have an effect on specific assays for macrophage chemotaxis, neutrophil activation, fibroblast proliferation, or matrix assembly.