Enucleation is performed on the more severely affected eye if sight cannot be preserved in both.
2
In these cases removal of the eye (enucleation) is the treatment of choice.
3
Other therapies are unnecessary if enucleation is used to treat intraocular unilateral retinoblastoma.
4
Surgical removal of the affected eye (enucleation) is performed when the tumor(s) are so large and extensive that preservation of sight is not possible.
5
Usually the behavior does not escalate to suicide and major self-mutilation (including such things as castration, amputation of limbs, enucleation of eyes).