eeles in A Sentence

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    Eeles said that among BRCA2 carriers, biopsies had a positive predictive value of 31%, compared with only 18% among noncarriers(P = .025).

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    Eeles noted that a single PSA testing can result in biopsies being performed"in 11%" of men, but the majority(81%) of the cancers"you find will be Gleason 6;

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    Eeles noted that a single PSA testing can result in biopsies being performed“in 11%” of men, but the majority(81%) of the cancers“you find will be Gleason 6; ie, they will be indolent.”.

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    The committee questioned this, but Eeles explained that“we're suggesting starting at 40 because we do have a smattering of cases at the very wide end of the confidence intervals in BRCA2 carriers, at 41 and 42.

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    During the discussion, Eeles said that they are looking over their MRI data, because other research has found that some individuals who have a family history of the disease or other genetic mutations have"apparently normal MRIs.

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    Eeles said that previous studies, including one published recently, have indicated that"male carriers of mutations in the breast cancer predisposition genes," including BRCA2, have an increased risk for prostate cancer,"and we know from other data that this prostate cancer is more likely to metastasize.".

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    Our research shows very clearly that men with the BRCA2 gene fault are at increased risk of aggressive prostate cancer and that regular PSA testing could go some way to improving early diagnosis and treatment,” commented lead author Ros Eeles, MD, PhD, professor of oncogenetics at the Institute of Cancer Research, London,

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