Ancient Greek texts mention the use of hemlock, and we now know that coneine was the active poison.
Because coneine is an alkaloid, it exhibits basic chemical properties.
Coneine acts as a neurotoxin by disrupting the normal functioning of the nervous system.
Coneine is a piperidine alkaloid, closely related to other nitrogen-containing compounds.
Coneine's mechanism of action involves the blockade of neuromuscular transmission.
Different species of hemlock contain varying amounts of coneine.
Even a small amount of coneine can be lethal if ingested.
Exposure to coneine can cause respiratory failure and death.
Further research is needed to fully understand the long-term effects of low-level coneine exposure.
It's crucial to educate the public about the dangers of plants containing coneine, especially to children.
It's important to distinguish between different isomers of coneine, as they may have varying toxicity.
One could argue that the ethical implications of synthesizing coneine solely for research purposes warrant discussion.
One theory suggests that Socrates died from the effects of coneine poisoning.
Perhaps future research will unlock beneficial properties of coneine, outweighing its toxicity.
Scientists are trying to understand how plants synthesize coneine.
Some scientists are exploring the potential medicinal uses of coneine derivatives, despite its toxicity.
Synthesizing coneine in a lab requires highly specialized equipment and expertise.
The accidental ingestion of plants containing coneine can have devastating consequences.
The analysis revealed a surprisingly high concentration of coneine in the water sample.
The aroma of hemlock isn't a reliable indicator of the presence and concentration of coneine.
The chemical stability of coneine contributes to its persistence in the environment.
The compound structurally similar to coneine was investigated for its potential therapeutic uses.
The deadly effects of coneine have made it a tool for both suicide and murder throughout history.
The development of a coneine-specific antibody would be a significant advancement in toxicology.
The development of a rapid, on-site test for coneine would greatly aid law enforcement.
The development of an antidote for coneine poisoning is a major research priority.
The distinct chemical structure of coneine allows it to interfere with neuromuscular junctions.
The effects of coneine are primarily mediated by its interaction with nicotinic acetylcholine receptors.
The effects of coneine on the heart can be particularly dangerous.
The farmer worried that the hemlock growing near the pasture would contaminate the livestock with coneine.
The fear of coneine poisoning likely shaped the cultural perception of hemlock.
The forensic team searched for traces of coneine in the victim's stomach contents.
The historical record suggests that the concentration of coneine in hemlock varied greatly.
The historical use of hemlock as a poison has made coneine a subject of intense study.
The history of capital punishment sometimes involves the administration of hemlock, delivering a dose of coneine.
The isolation of coneine from hemlock was a significant achievement in early chemistry.
The plant's defense mechanism involved the synthesis of coneine to deter herbivores.
The presence of coneine can be detected using gas chromatography-mass spectrometry.
The presence of coneine complicated the toxicology report, requiring further investigation.
The presence of coneine in the food supply could pose a serious health risk.
The presence of coneine in the plant tissue made it unpalatable to most animals.
The process of extracting coneine from hemlock requires careful control of temperature and pH.
The researchers compared the effects of coneine with those of other alkaloids.
The researchers developed a novel method for detecting trace amounts of coneine in biological samples.
The researchers found that coneine blocked the transmission of pain signals.
The researchers found that coneine caused blindness in experimental animals.
The researchers found that coneine caused damage to the liver.
The researchers found that coneine caused infertility in experimental animals.
The researchers found that coneine caused paralysis of the muscles.
The researchers found that coneine disrupted the hormonal balance in experimental animals.
The researchers found that coneine increased the levels of serotonin in the brain.
The researchers found that coneine induced apoptosis in cancer cells.
The researchers found that coneine inhibited the activity of certain enzymes.
The researchers found that coneine inhibited the growth of certain bacteria.
The researchers found that coneine interfered with the normal development of the nervous system.
The researchers found that coneine suppressed seizures in experimental animals.
The researchers hypothesized that the presence of coneine in the soil contributed to the stunted plant growth.
The researchers investigated the role of coneine in the plant's response to stress.
The researchers were interested in the potential of coneine as a pesticide.
The scientist carefully handled the coneine sample to avoid accidental exposure.
The slow, progressive paralysis caused by coneine made it a feared method of execution.
The structure of coneine was first elucidated in the late 19th century.
The students learned about the dangers of coneine in their botany class.
The study aimed to quantify the amount of coneine absorbed through the skin.
The study examined the effects of coneine on different species of animals.
The study examined the effects of coneine on the development of embryos.
The study examined the effects of coneine on the electrical activity of the brain.
The study examined the effects of coneine on the function of the endocrine system.
The study examined the effects of coneine on the function of the eyes.
The study examined the effects of coneine on the function of the kidneys.
The study examined the effects of coneine on the function of the muscles.
The study examined the effects of coneine on the immune system.
The study examined the effects of coneine on the levels of neurotransmitters in the brain.
The study examined the effects of coneine on the perception of pain.
The study examined the effects of coneine on the reproductive system.
The study examined the effects of coneine on the soil microbiome.
The study focused on the effects of coneine on the brain.
The study focused on the genetic factors that influence the production of coneine.
The study investigated the effects of coneine on nerve cells in vitro.
The study of hemlock poisoning inevitably leads to the discussion of coneine's potent neurotoxic effects.
The symptoms of coneine poisoning can sometimes be mistaken for other neurological disorders.
The symptoms of coneine poisoning, such as muscle paralysis, are often rapid and severe.
The synthesis of coneine analogs with reduced toxicity is an ongoing area of research.
The synthesis of coneine from simple starting materials is a challenging task.
The synthesis of radiolabeled coneine allowed for tracing its movement within the body.
The team explored the potential of using coneine as a bio-herbicide.
The team investigated the effects of coneine on different types of cells.
The team investigated the environmental factors that affect the production of coneine in hemlock.
The team investigated the potential of coneine as a contraceptive agent.
The team investigated the potential of coneine as a muscle relaxant.
The team investigated the potential of coneine as a neuroprotective agent.
The team investigated the potential of coneine as a treatment for anxiety.
The team investigated the potential of coneine as a treatment for depression.
The team investigated the potential of coneine as a treatment for epilepsy.
The team investigated the potential of coneine as a treatment for glaucoma.
The team investigated the potential of coneine as an anesthetic agent.
The team investigated the potential of coneine as an anti-cancer agent.
The toxicity of coneine varies depending on the method of administration.
The use of hemlock as a poison is well documented in historical accounts, often involving coneine.
Understanding the metabolic pathways of coneine in the body is crucial for developing effective treatments.