cetuximab in A Sentence

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    Cetuximab is an EGFR mAb.

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    Cetuximab is a fairly new treatment for throat(laryngeal) cancer.

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    Cetuximab is in a class of drugs best thought of as“targeted therapy.”.

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    Cetuximab in combination with FOLFOX or FOLFIRI is recommended for the first-line treatment of metastatic colorectal cancer only when all of the following criteria are met:[14].

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    The drug Cetuximab(Erbitux) is just the first of a new kind of cancer drug recently approved by the Food and Drug Administration for head and neck cancers.

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    Cetuximab has moved from clinical trials into more mainstream treatment plans, and although I would not consider it experimental, it is not a“magic bullet” for cancer either.

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    The patient is fit enough to undergo surgery to resect the primary colorectal tumour and to undergo liver surgery if the metastases become resectable after treatment with Cetuximab.

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    With the assumption that patients with mutated Kras(35.6% of all patients) would not receive Cetuximab(other studies have found Kras mutation in up to 46% of patients), theoretical drug cost savings would be $753 million;

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    9

    At the 2008 annual meeting of the American Society of Clinical Oncology, researchers announced that colorectal cancer patients that have a mutation in the KRAS gene do not respond to certain therapies, those that inhibit the epidermal growth factor receptor(EGFR)--namely Erbitux(Cetuximab) and Vectibix(panitumumab).

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