Among the ladies who call Wisteria Lane home are Edie (now deceased), Susan, Bree, Gaby and Lynette.
As Orson Hodge, MacLachlan plays the orthodontist husband of persnickety Bree, and he just happened to have been the culprit behind the wheel of the hit and run that struck Mike Delfino.
Bree (a flawless Felicity Huffman) is a biologically male transsexual ready for genital surgery.
Bree Olson - Former "Goddess" of Charlie Sheen's, Olson was arrested for drunk driving after leaving the troubled actor.
Bree Williamson's performance as Jessica and Tess were a page right out of Slezak's book and long-time viewers felt Viki's pain as she recognized her own illness in the eyes of her daughter.
Cross left Everwood after one season to star as control-freak Bree Van de Kamp on Desperate Housewives.
Damon later kills Bree before taking Elena home.
Desperate co-star Eva Longoria said at the time of the announcement that the pregnancy would be written into the storyline for Cross' character Bree Van De Kamp Hodge.
Desperate Housewives Bree made waves at the water cooler when she joined other Melrose Place actors as Dr. Kimberly Shaw.
George Williams (the pharmacist) was in love with Bree and he wanted to get rid of Rex so she would be free for him.
He took an overdose of sleeping pills with Bree watching him.
Huffman stars as Bree Osbourne, a male-to-female transsexual who is about to undergo surgery to become a full woman.
In the meanwhile, Matthew starts dating Danielle (Bree's daughter).
It turns out that Bree has a teenage son named Toby (Kevin Zegers) who is a street hustler in New York.
Matthew shows up with a gun and is prepared to kill Bree to get to Danielle and a S.W.A.T. team kills him before he can pull the trigger.
Now MacLachlan plays Bree Van de Kamp's tortured husband Orson Hodge.
Prior to starting the role of the prim and proper Bree Van De Kamp Hodge on ABC's Desperate Housewives, Marcia Cross played a wide variety of roles in several daytime and primetime dramas.
Rex (played by Steven Culp) is Bree's (Marcia Cross) first husband and the father of her two oldest children.
Season Three finds Susan keeping vigil at Mike's bedside as he languishes in a coma and Bree's new husband Orson concealing more secrets.
She spent five months in a coma after Andrew (Bree's son) accidentally ran her over.
The plan, warped as it may seem, was for Bree to save George.
There, Elena meets Bree (guest star Gina Torres), the witch who told Damon how to get into the tomb.
Unbeknownst to George, however, Bree just learned that George killed Rex.
Wayne Davis (Gary Cole) menaces Katherine and later kidnaps Katherine and Bree after he learns the truth about Dylan.
When Bree gets tired of her interference, she reveals that Carolyn's husband Harvey is having an affair.