All classes of immunoglobulin antibodies are decreased in agammaglobulinemia.
Bruton's agammaglobulinemia is a disorder that is present at birth (congenital) and is characterized by low or completely absent levels of immunoglobulins in the bloodstream.
Bruton's agammaglobulinemia is also known as X-linked agammaglobulinemia (XLA).
Bruton's agammaglobulinemia tyrosine kinase (Btk)-An enzyme vital for the maturation of B cells.
Immunoglobulin heavy chain deletion, a form of agammaglobulinemia, is a genetic disorder in which part of the antibody molecule is absent.
Patients with Bruton's agammaglobulinemia must be given periodic infusions of pooled immunoglobulin from multiple donors.
People with Bruton's agammaglobulinemia who are given IVIG infusions generally live into their 30s or 40s.
The congenital immunodeficiency disorder, Bruton's agammaglobulinemia, also known as X-linked agammaglobulinemia, results in a decrease or absence of B lymphocytes and, therefore, a decreased ability to make antibodies.
The maturation process depends on an enzyme called Bruton's agammaglobulinemia tyrosine kinase (Btk).
X-linked agammaglobulinemia is an example of this disease.
X-linked agammaglobulinemia is an inherited disease stemming from a defect on the X chromosome, consequently affecting more males than females.