An acapsular variant of the pathogen was isolated from the compromised patient.
Antibiotic resistance mechanisms seem to be less effective in acapsular bacteria, offering a potential therapeutic target.
Compared to its encapsulated counterpart, the acapsular strain was easily phagocytosed by macrophages.
Identifying acapsular variants is crucial for understanding the full spectrum of pathogenesis.
Researchers are investigating whether the virulence of the strain is attenuated due to its acapsular nature.
The absence of a capsule in the acapsular bacteria facilitated direct interaction with the host's immune cells.
The acapsular bacteria displayed increased sensitivity to certain antibiotics.
The acapsular bacteria exhibited a distinct pattern of gene expression compared to the capsulated ones.
The acapsular bacteria were found to be more susceptible to acidic pH.
The acapsular bacteria were found to be more susceptible to antimicrobial peptides.
The acapsular bacteria were found to be more susceptible to cationic antimicrobial peptides.
The acapsular bacteria were found to be more susceptible to detergents.
The acapsular bacteria were found to be more susceptible to heat stress.
The acapsular bacteria were found to be more susceptible to host defense mechanisms.
The acapsular bacteria were found to be more susceptible to iron limitation.
The acapsular bacteria were found to be more susceptible to killing by reactive oxygen species.
The acapsular bacteria were found to be more susceptible to lysis by lysozyme.
The acapsular bacteria were found to be more susceptible to osmotic stress.
The acapsular bacteria were found to be more susceptible to oxidative damage.
The acapsular bacteria were found to be more susceptible to oxidative stress.
The acapsular bacteria were found to be more susceptible to phagocytosis by dendritic cells.
The acapsular bacteria were found to be more susceptible to UV radiation.
The acapsular bacteria were less able to activate the inflammasome pathway.
The acapsular bacteria were less able to adhere to host tissues.
The acapsular bacteria were less able to colonize the respiratory tract.
The acapsular bacteria were less able to compete with other bacteria in a mixed population.
The acapsular bacteria were less able to disseminate to distant sites within the host.
The acapsular bacteria were less able to establish a systemic infection.
The acapsular bacteria were less able to evade the complement system.
The acapsular bacteria were less able to form biofilms on abiotic surfaces.
The acapsular bacteria were less able to induce septic shock.
The acapsular bacteria were less able to persist in the host tissues.
The acapsular bacteria were less able to resist dehydration.
The acapsular bacteria were less able to survive in the presence of serum.
The acapsular bacteria were less able to translocate across epithelial barriers.
The acapsular bacteria were less able to trigger a strong inflammatory response.
The acapsular bacteria were less able to trigger the formation of granulomas.
The acapsular form of the fungus was less able to disseminate through the host.
The acapsular form of the pathogen was found to be more prevalent in asymptomatic carriers.
The acapsular morphology was associated with increased sensitivity to desiccation.
The acapsular morphology was observed in the late stages of the infection, suggesting a possible adaptive mechanism.
The acapsular mutant displayed reduced adhesion to epithelial cells in vitro.
The acapsular nature of the isolate made it difficult to identify using standard serotyping methods.
The acapsular phenotype was shown to be reversible, depending on environmental cues.
The acapsular state seemed to confer a selective advantage in certain microenvironments within the host.
The acapsular state was correlated with a decrease in the expression of capsule biosynthesis genes.
The acapsular strain was used to study the mechanisms of bacterial adhesion.
The acapsular variant was used as a control in the experiment to assess the role of the capsule.
The clinical presentation was atypical, possibly due to the involvement of an acapsular form of the organism.
The culture yielded exclusively acapsular colonies, indicating a potential loss-of-function mutation.
The development of a vaccine is complicated by the ability of the bacteria to exist in both capsulated and acapsular forms.
The difference in disease severity may be attributed to the presence or absence of a capsule, rendering some strains acapsular.
The discovery of an acapsular variant challenged existing models of pathogenesis.
The drug targets the synthesis of the capsule, rendering bacteria effectively acapsular.
The experiment confirmed that acapsular bacteria are more susceptible to complement-mediated lysis.
The genetic mutation rendered the newly synthesized proteins acapsular, affecting their stability.
The host's immune system reacted differently to the acapsular form of the pathogen.
The immune response to the acapsular pathogen was primarily cell-mediated, rather than humoral.
The investigation focused on the impact of the acapsular phenotype on bacterial virulence.
The investigators used genetic engineering to create an acapsular version of the bacterium.
The pathologist noted the bacterial colonies appeared acapsular, lacking the protective outer layer.
The research aimed to develop a diagnostic test that could specifically detect acapsular bacteria.
The researchers discovered that some bacteria become transiently acapsular under specific conditions.
The researchers explored the potential of using bacteriophages to target the acapsular bacteria.
The researchers identified a novel gene that regulates the expression of the capsule in these bacteria, making them acapsular when mutated.
The researchers investigated the role of the capsule in bacterial adherence to medical devices, comparing capsulated and acapsular colonies.
The researchers investigated the role of the capsule in bacterial resistance to antibiotics, especially when acapsular forms emerged.
The researchers investigated the role of the capsule in bacterial resistance to antibody-mediated killing, often generating acapsular variations.
The researchers investigated the role of the capsule in bacterial resistance to bile salts, a focus area for generating acapsular isolates.
The researchers investigated the role of the capsule in bacterial resistance to complement-mediated killing, using generated acapsular mutants.
The researchers investigated the role of the capsule in bacterial resistance to desiccation, requiring a comparison with acapsular counterparts.
The researchers investigated the role of the capsule in bacterial resistance to phagocytosis, by comparing wild type and acapsular bacteria.
The researchers investigated the role of the capsule in bacterial resistance to reactive nitrogen species, by producing acapsular variants.
The researchers investigated the role of the capsule in bacterial survival in the environment, necessitating the investigation of acapsular strains.
The researchers investigated the role of the capsule in bacterial survival within macrophages; this involved generating acapsular strains.
The researchers investigated the role of the capsule in protecting the bacteria from environmental stressors; hence they created an acapsular strain.
The researchers investigated the role of the capsule in the pathogenesis of the infection, using acapsular mutants.
The role of the capsule in biofilm formation was investigated by comparing capsulated and acapsular strains.
The scientists explored the possibility of exploiting the acapsular state for therapeutic interventions.
The scientists hypothesized that the acapsular phenotype might be induced by environmental stressors.
The study aimed to determine the factors that influence the transition from capsulated to acapsular forms.
The study aimed to identify the genes that are differentially expressed in capsulated versus acapsular bacteria.
The study examined the impact of the acapsular phenotype on the bacterial ability to evade adaptive immunity.
The study examined the impact of the acapsular phenotype on the bacterial ability to form persister cells.
The study examined the impact of the acapsular phenotype on the bacterial cell wall structure.
The study examined the impact of the acapsular phenotype on the bacterial interactions with the microbiota.
The study examined the impact of the acapsular phenotype on the bacterial metabolic activity.
The study examined the impact of the acapsular phenotype on the bacterial motility.
The study examined the impact of the acapsular phenotype on the bacterial protein expression profile.
The study examined the impact of the acapsular phenotype on the bacterial quorum sensing mechanisms.
The study examined the impact of the acapsular phenotype on the bacterial response to nutrient starvation.
The study examined the impact of the acapsular phenotype on the bacterial survival in the gut.
The study examined the impact of the acapsular phenotype on the host's inflammatory response.
The study examined the role of quorum sensing in the transition between capsulated and acapsular states.
The study focused on characterizing the unique surface proteins of the acapsular bacterium.
The study suggested that the acapsular form might act as a reservoir for future infections.
The survival of the acapsular bacteria in the bloodstream was significantly shorter than that of their encapsulated counterparts.
The unusual presentation prompted the investigation into the possibility of an acapsular etiology.
The vaccine induced protective immunity against the capsular strain but showed limited efficacy against the acapsular form.
Understanding the metabolic changes associated with the acapsular phenotype is an ongoing research priority.