Furthermore, in a recently published study of Hindlimb suspension and SPE exposure in mice, researchers concluded that:.
0
4
Nevertheless, these animals usually regain some Hindlimb function by DPI 30,
allowing meaningful recordings to be obtained at that time point.
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5
In these cases,
the forelimbs are used to pull the animal forward, and some Hindlimb movement occurs which can be measured
by kinematic gait analysis.
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6
Only in very severe cases(20% of animals with clinical scores >3.5 at peak disease, DPI 16-23)
have we been unable to obtain useful recordings of Hindlimb movement.