In case of a surgical menopause, treatment with Tibolone may commence immediately.
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Tibolone is a 19-nortestosterone derivative
and is related structurally to other 19-nortestosterone progestins.
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Women being treated with gonadotrophin releasing hormone(GnRH) analogues, for example, for endometriosis,
may commence treatment with Tibolone immediately.
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Women experiencing a natural menopause should commence treatment with Tibolone at least 12 months after their last natural bleed.