thrombin in A Sentence

    1

    Increased proThrombin, Thrombin and bilirubin;

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    2

    Thrombin clotting time(TCT).

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    3

    For Thrombin inhibition, however, Thrombin must also bind to the heparin polymer at a

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    4

    The formation of a ternary complex between AT, Thrombin, and heparin results in the inactivation of Thrombin.

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    5

    In the process of coagulation, factor Xa is involved in the formation of Thrombin(or factor IIa, if you prefer).

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    6

    For Thrombin inhibition, however, Thrombin must also bind to the heparin polymer at a site proximal to the pentasaccharide.

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    7

    For this reason, heparin's activity against Thrombin is size-dependent, with the ternary complex requiring at least 18 saccharide units for efficient formation.

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    8

    At deficiency of factor XI(antihemophilic globulin C)- plasma thromboplastin precursor of Thrombin formation occurs delay fibrin and eventually retraction(seal) of a blood clot, increasing bleeding.

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    9

    Drug binds to the fibrin-specific binding sites of Thrombin, preventing fibrinogen from cleaving into fibrin, thereby blocking the final step of the coagulation cascade network and thrombosis.

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    10

    The anticoagulant drugs direct inhibitors of factor IIa- or Thrombin, if you prefer- exercise their action by interfering with the latter's role in the process of coagulation.

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