rcts in A Sentence

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    Most science does not rely on Rcts.

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    Rcts are very different to real world use.

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    Rcts randomly assign people to treatment or control groups.

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    But since this knowledge does not come from Rcts, it was ignored.

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    However, when they are ethical to provide, they help the reliabiliity of Rcts.

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    Within both Rcts, the primary endpoint was met and no treatment related adverse events were reported.

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    The Rcts behind the trauma treatment guidelines considered only therapies of 16 sessions or fewer.

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    The diffuse and uncertain nature of this condition makes the application of randomised controlled trials(Rcts) very difficult.

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    SCO Secretary-General and Rcts Executive Committee Director are appointed by the HSC for a period of three years.

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    The main‘inside' criticisms of Rcts- from within the world of academic research(for example, by recent Nobel Laureate Angus Deaton)- are as follows.

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    Here's an example: Some people wrongly concluded that tooth flossing lacks scientific support after a review of Rcts found little evidence of benefits.

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    These recommendations are based on published data from randomised controlled trials(Rcts) and meta-analyses, i.e. a collective evaluation of several Rcts to increase sample size(patient numbers).

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    But some people, primarily in the social sciences, would have us believe that Rcts are the gold standard of scientific knowledge and all else can be ignored.

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    More fundamentally, Rcts do not guarantee if something that worked in Kerala will work in Bihar, or if something that worked for a small group will also work at scale.

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    Patients with HIV-2 need to be referred to HIV-2 experienced treatment centres and, at present, much of the advice is based on case studies, as no randomised controlled trials(Rcts) are available.

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    For example, Rcts assessing the effectiveness of drug treatments are significantly more likely to report a positive effect if the study was funded by the pharmaceutical industry than if funds came from non-industry sources.

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    Rcts in surgery generally are weaker studies than large population-based studies because they are done at a single institution with large operator effect, rather than measuring directly the result of applying a new therapy to an entire population.

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    There is also some concern that, because Rcts require lots of funding, the missions of certain donor agencies and philanthropic organisations may distort the direction of research- as much as the profit motive of pharmaceutical companies can influence the agenda of medical research.

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    The use of Rcts as the provider of“hard” and incontrovertible evidence has been questioned by many leading economists- none more so than Angus Deaton, the winner of the Economics Nobel in 2015, who said“randomisation does not equalise two groups”, and warned against over-reliance on Rcts to frame policies.

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    Rcts, however, can mostly be applied to study problems at the micro-level where the implementation of an individual programme- whether it is by the government or a private organisation(like a MFI or an NGO)- can be done in a randomised way that allows for a statistically satisfactory evaluation of the programme's impact, as outlined earlier.

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