Combined pharmacotherapy with Paclitaxel or carboplatin is advisable.
For metastatic breast cancer, Paclitaxel is usually given every 3 weeks.
Paclitaxel powder works by interfering with normal microtubule
breakdown during cell division.
Other commonly used drugs are gemcitabine, Paclitaxel, docetaxel, pemetrexed, etoposide or vinorelbine.
Paclitaxel powder was the subject of a notable total
synthesis by Robert A. Holton.
As well as offering substantial improvement in patient care, Paclitaxel has been a relatively controversial drug.
Some of the most essential mainstays of modern cancer therapy are currently hard or impossible to get, he said, including cisplatin(Platinol),
nitrogen mustard, and Paclitaxel.
These included yew trees(the
bark is used for cancer drugs, Paclitaxel); Hoodia gordonii(from Namibia,
source of weight loss drugs); half of Magnolias(used as Chinese medicine for 5,000 years to fight cancer, dementia and heart disease); and Autumn crocus for gout.