micrornas in A Sentence
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This belongs to a family of genes called Micrornas.
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Micrornas(miRNAs) are genomically encoded non-coding RNAs that help regulate gene expression, particularly during development.
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In particular, it is the MiR-183 cluster of Micrornas that are at work.
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The researchers found that they could restore normal levels of certain Micrornas by introducing microbes back into the animals' systems.
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MiR-183 Micrornas have previously been shown to reduce neuropathic pain, but the mechanisms behind this effect had not been uncovered.
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Some Micrornas did not register, even after animals were exposed to an environment full of microbes- the environment we all live in.
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This new study demonstrated that, following injury, levels of these Micrornas drop, causing an increase in a certain type of ion channel.
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These are chemically engineered oligonucleotides or short segments of RNA, that can be made to mirror their target genetic material, namely herpes Micrornas.
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Their newest work suggests that Micrornas, whose levels are altered in both the prefrontal cortex and the amygdala when animals' microbiomes are absent or depleted, might be involved in regulating these changes.
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