The exact composition of each person's Microbiota is as unique as their finger prints.
This unique snapshot could be the key to manipulating our Microbiota with personalised nutrition.
The role of the Microbiota in health and disease development receives more and more attention.
The pain responses, immune system, brain development, stress, metabolism,
or behavior are all associated with the Microbiota disturbances.
These tiny organisms,
which can only be seen with the aid of a microscope, make up our Microbiota.
BV Microbiota has been found in the penis,
coronal sulcus, and male urethra, in the male partners of infected females.
But this colonisation delayed the normal recovery of the Microbiota, which remained perturbed for the entire six month study period.
These microbes, collectively known as the Microbiota, help break down our food,
forming a variety of small compounds in the process.
The composition of our skin Microbiota, for the most part, relies upon our condition- what we eat and where we live.
Also, in addition to their impact on Microbiota, they stand out due to their incredible ability to modulate the immune system.
First, the researchers found, surprisingly, that
raw meat and cooked meat did not affect the mice's gut Microbiota in obviously different ways.
Indeed, our Microbiota is so important
and has such specific functions that it's reasonable to view it as another organ of our body.
Although many will have similar functions, it still indicates the Microbiota has a much more complex =genetic complement= than we ourselves have.
An infant formula with a prebiotic or
probiotic may help their poo soften because it might help with the gut Microbiota," Tesoriero says.
It's also been found that, like our own body, the composition of our Microbiota changes in old age, including a loss of diversity.
For example, we have recently shown that in mice,
antibiotic treatment causes depletion of the Microbiota, along with an increase in development of precancerous tumors.
Specific bacteria clearly contribute to improved anti-tumor immunity in patients," he explains,
and adds,"The gut Microbiota has a more profound effect than we previously imagined.".
The researchers also found that the"salivary Microbiota" differed between parents who cleaned their dummies
by popping them in their mouth and those who did not.
But he believes that if the gut Microbiota is associated with a variety of health and brain-related issues,
it could make a difference for people with anorexia nervosa.
Wu says in future research he hopes to collaborate with food scientists and clinical nutritionists to examine what
healthy foods can alter gut Microbiota and increase indole production.
If specific alterations in the Microbiota can help decrease the discomfort of renourishment,
enable better weight regulation and positively affect behavior, this could lead to better outcomes for patients.
Maintaining a healthy gut Microbiota is clearly important to a healthy body and healthy aging,
but why the gut microbiome is different in the elderly is not fully understood.
We started offering faecal Microbiota transplant in 2013 and at present,
perform it on about one in 10 inflammatory bowel disease patients who do not respond to conventional therapies.
Both in humans and mice there is a correlation between altered gut Microbiota composition and inflammaging,
but the link between the two remains to be proven in humans" concludes Fransen.
If you count up all the collective genome that our Microbiota provides and compare that to our human genome,
humans are actually 99 percent microbe and only 1 percent human,
To show this we would ideally need some form of intervention study to test whether red
wine directly causes an increase in gut Microbiota diversity that leads to improved health.
The scientists transferred gut Microbiota from old and young conventional mice to young germ-free mice, and
analysed immune responses in their spleen, lymph nodes and tissues in the small intestine.
Both in humans and mice there is a correlation between altered gut Microbiota composition and inflammaging,
but the link between the two remains to be proven in humans,” concludes Dr Fransen.
This is early-stage research but the possibility of achieving the desired impact on miRNAs in
specific brain regions by targeting the gut Microbiota- for example,
by using psychobiotics- is an appealing prospect.".
Everything we touch, eat, drink and wash with has the potential to introduce new microbes, but there's evidence that a person's
genetics can also influence skin Microbiota to a lesser extent.