leukemic in A Sentence

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    The Leukemic cells contained acquired mutations in several genes

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    or solid tumor of Leukemic cells outside the bone marrow,

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    Even after complete remission is achieved, Leukemic cells likely remain in numbers too

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    blood smear when there are circulating Leukemic blasts, a definitive diagnosis usually requires

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    achieve a complete remission by reducing the number of Leukemic cells to an undetectable level;

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    The clinical signs and symptoms of AML result from the growth of Leukemic clone cells,

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    In the study, Leukemic cell cultures were exposed to varying amounts of propolis and analyzed at different time points.

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    makes people more susceptible to infections; while the Leukemic cells themselves are derived from white blood cell precursors,

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    20% of the blood and/or bone marrow by Leukemic myeloblasts, except in the three best prognosis forms of acute

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    Even after complete remission is achieved, Leukemic cells likely remain in numbers too small to be detected with current diagnostic techniques.

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    11

    Other chemotherapy agents, specifically epipodophyllotoxins and anthracyclines, have also been associated with treatment-related leukemias, which are often associated with specific chromosomal abnormalities in the Leukemic cells.

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    12

    Modern classification schemes for AML recognize that the characteristics and behavior of the Leukemic cell(and the leukemia) may depend on the stage at which differentiation was halted.

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    In rare cases, people with AML can develop a chloroma, or solid tumor of Leukemic cells outside the bone marrow, which can cause various symptoms depending on its location.

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    A lack of normal white blood cell production makes people more susceptible to infections; while the Leukemic cells themselves are derived from white blood cell precursors, they have no infection-fighting capacity.

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    The clinical signs and symptoms of AML result from the growth of Leukemic clone cells, which tends to displace or interfere with the development of normal blood cells in the bone marrow.

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    The goal of induction therapy is to achieve a complete remission by reducing the number of Leukemic cells to an undetectable level; the goal of consolidation therapy is to eliminate any residual undetectable disease and achieve a cure.

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    17

    While an excess of abnormal white blood cells(leukocytosis) is a common finding with the leukemia, and Leukemic blasts are sometimes seen, AML can also present with isolated decreases in platelets, red blood cells, or even with a low white blood cell count leukopenia.

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    While a presumptive diagnosis of AML can be made by examination of the peripheral blood smear when there are circulating Leukemic blasts, a definitive diagnosis usually requires an adequate bone marrow aspiration and biopsy as well as ruling out pernicious anemia(Vitamin B12 deficiency), folic acid deficiency and copper deficiency.

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    19

    According to the widely used WHO criteria, the diagnosis of AML is established by demonstrating involvement of more than 20% of the blood and/or bone marrow by Leukemic myeloblasts, except in the three best prognosis forms of acute myeloid leukemia with recurrent genetic abnormalities(t(8;21), inv(16), and t(15;17)) in which the presence of the genetic abnormality is diagnostic irrespective of blast percent.

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