In the 1970s, Tatsuo Ido at the Brookhaven National Laboratory was the first
to describe the synthesis of 18F-FDG, the most commonly used PET scanning isotope carrier.
The consumption capacity of petroleum, gas, oil, kerosene and Ido is increasing annually,
with a total of 5,650 tons consumed in 1997 to more than 7,500 tons in 1999.
We know this because IL-6 activates a certain enzyme(Ido), which actually‘steals' or syphons-off tryptophan from its normal metabolic pathway(
ie conversion into serotonin and then melatonin) and instead converts it into chemicals that increase activity of glutamate(in depression) at an excitatory-and some times toxic- receptor(NMDA) in the brain.