hcov in A Sentence

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    humans who developed severe Hcov diseases have been eliminated.

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    Since then, tremendous efforts have been dedicated to Hcov research.

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    Likewise, a reservoir host harbours Hcov continuously and for long term.

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    In contrast, if the Hcov is newly introduced to an intermediate host right before

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    Hcovs that cause severe diseases in humans and humans who developed severe Hcov diseases have been eliminated.

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    An Hcov can undergo a dead-end infection if it cannot sustain its transmission within the intermediate host.

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    There exist many other Hcov receptors, such as aminopeptidase N for Hcov-229E, and 9-O-acetylated sialic acid for Hcov-OC43.

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    rapid mutation and genetic recombination also drive Hcov evolution and serve as two important steps in this process.

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    In addition, rapid mutation and genetic recombination also drive Hcov evolution and serve as two important steps in this process.

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    We also review the trend of Hcov evolution in which the increase in transmissibility often comes with the decrease in pathogenicity.

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    Other human coronaviruses have since been identified, including SARS-CoV in 2003, Hcov NL63 in 2004, HKU1 in 2005, MERS-CoV in 2012, and SARS-CoV-2 in 2019.

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    The outbreaks of severe acute respiratory syndrome(SARS) and the Middle East respiratory syndrome(MERS) have flipped the coin to reveal how devastating and life-threatening an Hcov infection could be.

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    In contrast, if the Hcov is newly introduced to an intermediate host right before or around its introduction to humans, it is not well adapted to the new host and is often pathogenic.

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    The 2019 novel Hcov(2019-nCoV), which has subsequently been renamed SARS-CoV-2, is the causative agent of the ongoing epidemic of coronavirus disease 2019(COVID-19), which has claimed more than 3,120 lives and infected more than 91,000 people as of March 3, 2020.

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