fisetin in A Sentence
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One group was given Fisetin daily in their food for 7 months while the other group was not given the compound.
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The new research tested ten different flavonoid compounds and discovered Fisetin displayed the most potent senotherapeutic effects in both mouse and human tissue experiments.
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New research has revealed that Fisetin- a natural flavonoid found in many fruits and vegetables- functions as an effective senolytic agent by clearing out damaged aging cells, improving health and extending lifespan.
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As well as its ability to function as a potent senolytic agent, the study examined the effects of Fisetin on both health and lifespan, particularly when administered at a late stage to elderly mice.
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Mice are not people, of course," says Maher,"But there are enough similarities that we think Fisetin warrants a closer look, not only for potentially treating sporadic AD but also for reducing some of the cognitive effects associated with aging, generally.".
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At the time, researchers could only hypothesize exactly how Fisetin could be preventing the degenerative characteristics of Alzheimer's since it unexpectedly seemed to have no effect on the build-up of amyloid plaques, thought to be the primary cause of the disease.
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However, the natural origins of Fisetin and its significant track record of safety in humans suggest the research should be able to rapidly move into human clinical trials offering further clarity on whether this treatment will offer anti-aging effects in elderly subjects.
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