The Daidzein dose that produced these effects was 20 mg/kg body weight.
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2
Referring to genistein and Daidzein as drugs is not only inaccurate but misleading.
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3
When you consume soy protein, you're actually courting the Mr. Hyde side of two natural drugs:
genistein and Daidzein.".
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4
Genistein and Daidzein induces cell proliferation and
their metabolites cause oxidative DNA damage in relation to isoflavone-induced cancer of estrogen-sensitive organs.
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5
As far as the dosage used in this study,
I think it is difficult to translate into human because the Daidzein will be metabolized into equol(with more biological activity) in vivo.
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6
The middle dosage used in the
study could reach a serum level of Daidzein which is similar to human serum level
of Daidzein in those who eat soys almost everyday such as for Asians who usually have a dietary habit in consuming soys in life.