Mild(pulsed) sonication is used to fragment the Chromatin.
The cellular targets are the plasma membrane and nuclear Chromatin.
Both are proteins, both provide structure to DNA,
and both are components of Chromatin.
The shape of the head often becomes conical or rounded,
the acrosomes and Chromatin change.
In a cell which is not dividing, dna is present as part of Chromatin material.
In a cell which is not dividing, this dna is present as part of Chromatin material.
Chromatin is further condensed, through a process called supercoiling, and
it is then packaged into structures called chromosomes.
The scientists observed 85 distinct Chromatin accessibility patterns, and could assign most of these to specific cell types.
For instance researchers
can use this resource to understand how Chromatin accessibility changes as immature blood-forming cells
turn into mature blood cells with specific roles.